HsaINT0132933 @ hg19
Intron Retention
Gene
ENSG00000164099 | PRSS12
Description
protease, serine, 12 (neurotrypsin, motopsin) [Source:HGNC Symbol;Acc:9477]
Coordinates
chr4:119229591-119234552:-
Coord C1 exon
chr4:119234356-119234552
Coord A exon
chr4:119229733-119234355
Coord C2 exon
chr4:119229591-119229732
Length
4623 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
ACTTTTGAATCATGACTTAGGTT
3' ss Score
5.95
Exon sequences
Seq C1 exon
ATATGGTAAACAAGCATCTGCCAACCATTTTGAAGAAAGCACAGGGCCCATATGGTTGGATGACGTCAGCTGCTCAGGAAAGGAAACCAGATTTCTTCAGTGTTCCAGGCGACAGTGGGGAAGGCATGACTGCAGCCACCGCGAAGATGTTAGCATTGCCTGCTACCCTGGCGGCGAGGGACACAGGCTCTCTCTGG
Seq A exon
GTGAGGACTGGCTGCAGCTCTCAAGTTTCCATCATTCAGTAGCCATTGCACCTCTAACCACTGGCCTTGAATATGAAGTGTTTCTCATCTTTGGCTTTTTTTGGGGTCTATTTCCCATAACTGTCTAATTTTCAGTAATTTTTATGCAGAGAAAAATAATCTTTTGAGTCTGTGCGCCAACATTATGAAATTTCTACCCCTAAATTGTTTTTCTTTACTTAGAAAATTAAGTTCCTCACTAACAATGTTTACAATCATCTGTATCTGAAAAATGGAATAAAGAAGCTGCAGTATCTATTCCCCTTACTCCTCGGTCACTTATTCTGATTTTCATTTACCTTGAATTCTAGTGAGCTATTTGGGATAGGATTTAAAATAAGAATATTCTCCTCTCCCTGTCTCATGGTTCATTTCTTCTCTAGTCCTGAAGCCTTGTCGTTCGTTGGTCACCAACCATCCATTGCTCTTTTAAGTGTCTCAGTGGTCTTCTAAGTGGATTAATTAAAGTTAATAGCTCACCCATCTTTCTAGTGTAACTTGTTATTTTAGAAACCCATCAGGGACCTCTGTTACTCTTCATTTACATTTTTTTAGACTTTTTGGATAAAAGGTAACTAGCTCCTCTAACTGTATTGAAATAATTATAGATAAAGATCCTCTTGAGAGTAGATAGCAGTTAAACATTCTTGATAAATTTCTTAATGTCTGATGAGGAGGGCAGAATATATATGAATGAAAAATACAGAGGGAAATATTCAAAATACTTTGTTGTATGCTATCACAGCTTTATTATATATCTATCTGTGTGTATGTGTATGTGTGTGCGTGTGTGTGTGTGTGTATGTGTATGAATAGATGTTAAAATAGCCTTAGGTGGTCTTTACTTTTAACCTTGGATTGAATCAACTCCTTTGTATTCTCCTGTTTGGAGACTGTGAAGCTGAAATCTTCATGTTATAAAGTAACAACTTTTTGAACCTCAGAGTATTAACCATATTACATACTTTAAATTTGTCAGAGTCTGTGGCTGATTCCTCATTGTACTGTACACTGTGAGAGCTTGGTGACACTGCATTAATCTAGCATTATACCAAGTTGAAATACATGTTTTTATTCCATCTCTTGCAGGCCATATTTCCATTTTTCTTTCTTTTCATTTTGTTCTCCTTTTCCCTTGCCCCTTCTTTTGAAAGATTTGTGATCCTCCCAGGATTATGTGGTGGATGTGGTTGAGGGAGATAGAATTTGTTTGCTGGAGATGGATTCTCTCAGCCCCAGATAGCAGGTGTTGGAATCATGGGATGATCTACGCAGATATGCTCTGTGAGCTCCCAGTGATGAAATACTATGTGACCTGAGTTCTCTGTAGGCCTGTGTTGTTAAACACATCATATGGTTGGAATAACTAATCTTTTCTGTTCCCTTGAAAATCTTTTTAATTCTAGGACTCTAGATGTATTTTTAAAAAATTTAAAAACCTGAGGGTGATAATTATTAATAAAATATATGATCACTATTATGAATCTCTTTGGTTCTAATCTCAGTAATGTGTCTATTAACTAAAGTCATTTGTCTGAAGAACATTATATCTGAGCCAAATATCCTTTTGGGATAGAATCATATTACTATTTGTTCATTCATAGATCATTACTTCCACCTATTAAAAACTACTATATATTTAAAAGGGAAGCTTAGAGGAGGAGATAACAGGATAACAATATAAATAACAGCATTTAGGAAACAATGGAGATTTTTTACTTCTTTGGCACTGCAATGATGAGCTCTTGGACTACTGCTGTTTTCAGCTATTTGAAGGCTAATTTCTGGACCTTAACTTTATATGTCAAGGGAAACTTCTCAAAATTAGTTATAGCCCTGTAGACACTCTTTTGGGTCTGTGGTAGGTGAAATGCTCAAAAGCAGTATTCTAGATTAGTAAAAGTAATTCTAGTAAGAATACAGTTATGTGAGTTGGCAGAAATTTCTGGGATGGTAAAAATATGGATTTCTCGTTTTAATATTACATTAATTCTAAAGTTCAGAGTATTAAGTCCTGGCAAAGATTTCTTTCCCAGTGAGGTTGTTGCCTCTTACTCAATTTTACAGTATAAAATTAGGCTTAATTTAATTAATTAATTAATTAATTAATTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCACCTCCCGGATTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTATCTGGGATTACAGGTGCCTGCCACCACACCCAGCTAATATTTGTATTTTTAGTACAGATGGAGTTTTGCCATGTTGGCCAGGCTGGCCCCAAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGAGCCTGGCCTAAAATTAGGCTTTTGCTGTGTATGTATGCATGTTAGAATTTATCTTTTTTCTAAAAGACAGTAGTATTTTATAAAAATAATGTATTATGTTACAGGAAAAATCAAAGAAAACTACTGAAAGCTTGAGATATATATTAAAGATAACTGTATACCAATATGATTGTTTAGCTTTTCCAAAAACTTTATATATTTAAGATTTTGGAAATAAAACATGCTATGTATTATTATTTCTGTAACAACACAAACTTAATAGTGACAACGTATGGATGGCATGACTTTTGTCATCCAGTTTCCCTTCAAGAATTAGGAATTTAATGATTTTGTAGAATGAATGGCTAAAATTAGGTTCAGAAATATTGTATGCATTATTTTTACAAAGCCATGCAAGTTATACTTTAAAAACACTTTATCATTTTTATTTTCAGAGTATATGAAAATGTGCCTGTAAAACTACCAGAATGGAACATGTAGATCTAATTTCATGTGCAAATGTTTTCTTAATTTTGAACCAAATATCCAAAAATATAAAAAGTGAAAACTTTAATAAAAGAATTTCATTTGTTTGATTTTGGTATCTGAGGATCACTTTTTCACTTTCTGTTCTTGCAAAGAACTCCCAAATTTCAGATGTATTAATGAGAAATATGAAGTTTCAATATTGTGTTTTATGACACAGCTAAAACTCCAAGTTTTTATCCAGCTGATAGTAAGCAGTGCATACATAGAGTTGGCACGCCATAAACATTTGTTGAGTTTGATTTTGCTCTGTGATTCCGCTATACTGCCTTGTCCCATGAAGTGAACATGATTAGGGATAGAGACTGGGGAGCCAACAACTCTTGGGGCAACACAGAAGGATGGAGAAGTAAAAAATGGGTCAGAAGAATAAAAATAGAGTGTGTCCATCTTGCTAACAATATTTTCTTTTAGTTAACCAATGTTGATTTAGTAACTTCACATATTGGTTTAAACATATATTAAATAATATATTGTCCATTACCTGCAGACTTCTACCTCCCTAGTTCTGCTAATAAGTTTACCATGCTTTATTGTATTCCCTAAATCCTTAACAGCAAATCTTGGCCCTGAAGCTGGAGACCCTTCTAGTAACTAGGTAATCAGATGTGTGAGTGTTAGCTTGCTTGGGTTGCTATAACAAAGTTCCACAGAGGTGACTTAAACACAGATGTTTATTGTTTCACAGTTTTGGGGGTTGGAGTCCACAATCAAATGTCAGTAGGGTTGGTTCCTTCAGAAAGAACTGTGAGGGAAGGGCTGTGTGAGAGAGAGAGATGCTCCAGGCCTCTCTCCTTAGCTTGTATATGGCAGTCCTCTCCCTGTGTCTCTTCACATCATCCTCTTCATGTCTAAATTTCTCAATTTTATGGGAATACCAACGTATTTGATTAGGGCTCACCCTAATGACCTCACAATTCAACCCATGCAAGTCACAGTGAGGAGTTTCGATTCAAAATCATAATTATTGGTGTGGTGATATGTGACACTTTACAAATCCCTTCATTTGTATTAACTTAGATAAATCTTAATTTGCTAGAGTTCAGTTTCTCAACTTTTAACTCAGTAATTTTTGTGACTTAATTCTTTCCCTTAAAATCAATAGAAAGCCTTAGATGGTAACTGTCCCTATTTACTGCTTTTTTTTTTCTTTTTCTTTTCTTTTTTTTGCCTCCTCCAGCATTAGACTTGAATCAAGTTACCCAACTATGAATGCCAAGATTGTGTCTATTTATATCGTTCTAAAAATCTTGTCTTTGGTGTATAAACTTCTAGCTCTCTGTTCATGGATAAATGAACAGACATGAAGCAGAAACAACCTCAAGTTAATGTTCTTTTACTATTTAGAAGTAAGGTGTAATAAAATAATTCACAGTTTTATAATGCTGTTCATTCATTCAACAAACAGCAATTGCATATCCTCTGTATGCCAGGCACTGTTCCACAGTCTGGGGATACAAGGTTGAGCAAGGTGAGCACTTTGAATTCAAGGCTGCAAGAGACATACAAAAGTGGATAAAATTTTTATTGATATATCTCCTCTCTCTCAAAAAAGTATTTCCCATCTGATTTTATAGCTGATTAAAAAGAACAATTGTGTTTTGTAGAGTCGCTCATGCTTTAGAATCAGTTTGCATGTTTGGGCTGTTCTAATACTTTTGAATCATGACTTAG
Seq C2 exon
GTTTTCCTGTCAGACTGATGGATGGAGAAAATAAGAAAGAAGGACGAGTGGAGGTTTTTATCAATGGCCAGTGGGGAACAATCTGTGATGATGGATGGACTGATAAGGATGCAGCTGTGATCTGTCGTCAGCTTGGCTACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164099-PRSS12:NM_003619:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PD(56.7=82.1)
A:
NA
C2:
PF0053013=SRCR=PU(41.8=85.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)