DmeALTA0005431-2/2 @ dm6
Alternative 3'ss
Gene
FBgn0029167 | Hml
Description
The gene Hemolectin is referred to in FlyBase by the symbol DmelHml (CG7002, FBgn0029167). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:13846054..13860001. Its molecular function is described by: protein homodimerization activity; chitin binding. It is involved in the biological process described with: chitin metabolic process; hemostasis; hemolymph coagulation; wound healing. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; immune response defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed at stages throughout the larval period.
Coordinates
chr3L:13847022-13847640:+
Coord C1 exon
chr3L:13847022-13847186
Coord A exon
chr3L:13847248-13847250
Coord C2 exon
chr3L:13847251-13847640
Length
3 bp
Sequences
Splice sites
5' ss Seq
GGGGTAATT
5' ss Score
5.8
3' ss Seq
TAAAATAAAATCTTCAACAGAAG
3' ss Score
3.67
Exon sequences
Seq C1 exon
TGCACGATACACTTATGGCGGTTCTGAAGGAGGCCGTAGTGGATTCGGAGGAGGATATGGTGTTGGTGGAGGTGGAGGTGGTGGTTATGGCGGGATAAAGACGTCTCATGCCGCTGGAGGACTGCTTACCAAAACCTTGGGCTTTTTAGGCATGGGTGGCCAGGG
Seq A exon
AAG
Seq C2 exon
TCAGGGCAACTTTTACGGAGGCGGAGGACACTTTCTAGCAGCCTTCGGAAAATGTTCAGCCCTCCAACTGCCGTCCAATGTTCAGTCTGAATGCCACAATGGTCGTTGCAAAGTCTTCTGCCCAACTGGCTATAGTTTCGCACAGGACGTTTCAGTCCTGGAGATGTTCTGCAGCAATGATGGATGGATCATAGGCAACTCCGTGTTTGCGGAGGTGCCACCCTGTCAGGCACAATGTACACCTCCATGCCAAAACAATGGCATCTGCATTTCCGCCGGAGTGTGCCAGTGTCCGGAGAACTACTACGGTCCGCTGTGTCAGCAAAAGAAGTCCATATGTGCATCCTTTCCGAAGGCACCGAAAAACTCCAAAGTATCCTGCAAGAACAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0029167-2-3,2-2-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF079748=EGF_2=WD(100=24.4)
Main Inclusion Isoform:
FBpp0075495
Main Skipping Isoform:
FBpp0305234
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGCTTTTTAGGCATGGGTG
R:
TGGAGGGCTGAACATTTTCCG
Band lengths:
94-97
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)