DmeALTA0005557-1/2 @ dm6
Alternative 3'ss
Gene
FBgn0010051 | Itp-r83A
Description
The gene Inositol 1,4,5,-trisphosphate receptor is referred to in FlyBase by the symbol DmelItpr (CG1063, FBgn0010051). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:5517117..5539411. Its molecular function is described by: calcium ion binding; phosphatidylinositol binding; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; inositol 1,4,5 trisphosphate binding. It is involved in the biological process described with 22 unique terms, many of which group under: behavior; response to nutrient levels; response to starvation; sensory perception; regulation of feeding behavior. 52 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; alimentary canal; cellular anatomical entity; developing material anatomical entity; organelle. The phenotypic classes of alleles include: phenotype; increased mortality; size defective; body size defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages.
Coordinates
chr3R:5517117-5527919:+
Coord C1 exon
chr3R:5517117-5517888
Coord A exon
NA
Coord C2 exon
chr3R:5527579-5527919
Length
0 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGT
5' ss Score
11.45
3' ss Seq
TCCTTTGCCAATCCCCGCAGGAC
3' ss Score
10.58
Exon sequences
Seq C1 exon
AAAAGTGCGTAGAAATCGACAATCGTTTTGTTTGCCCGCGCTGCTGCTGCGCTGCGACTGCGCTGCTTGTGGGTGGTCAACGGGATCGTGGGGTCGGGAGAGCCGATTGTTGACGTTGTATCGCATGCTGCCTCTCTTTCCCGCAGCCGGAATTGTTTGTCGCGTGTTTTAACGGTTATTTCTTATTGACAAAACCTCCTCTGCCGACGTCGCTGCCCCGGCATTGTTATTGTTATTGTGTGTGGTTTCTGGGCCTTCTTCTTCCTCCTCACCGTATTCCCACTTATTGTTATTCTCTCTTTTCCGCGGCTAAGTGCGGCCCACTCAAGGTGAAAATATATTAAGTTCTTTCGAGTGCCCGCGAGTGTTTGCATTTGAATAAAATAAATATAAAGTCAAATTCGATTTACGATCGTCGTCTATCGACGGATGATTCAATACCAATCACAATACAGTAGCACATCTCTACAAGGGATATTTTACATTACATACATTCTACG
Seq A exon
NA
Seq C2 exon
GACATAACGAGGTCGACAAACCAGTGCAATTAACTCGCGTAGCCGACTGCGCCTCCAAACAATAGCTCCCAGCTCCGGAACAGCTACGGCCAGAGAGCACAGCAACAGGCGCTGGCACGTGGGGAGCATCGGGTGGAGGCCCATTGTTGCGCCACCTGGCGGCAGCCACTGTACACATTCGGCACTCTCGACTTGGATACCATTCCCATCGCAAGCCCCAACCCACAGTGGGCTTCAGACATGGGCGACAATATAATTGGCTCGGCAAGCTTCCTGCACTTGGGGGACATTGTGTCCCTCTATGCGGAGGGCAGCGTTTGCGGTTTCTTGAGCACACTCGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0010051-2-1,2-0-1/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.000
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
PF087096=Ins145_P3_rec=PU(11.8=79.4)
Main Inclusion Isoform:
FBpp0078335
Main Skipping Isoform:
FBpp0310670
Other Inclusion Isoforms:
FBpp0078336
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGACGGATGATTCAATACCAA
R:
TATTGTTTGGAGGCGCAGTCG
Band lengths:
142-187
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)