DmeALTA0008004-2/2 @ dm6
Alternative 3'ss
Gene
FBgn0027594 | drpr
Description
The gene draper is referred to in FlyBase by the symbol Dmeldrpr (CG2086, FBgn0027594). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is 3L:1715595..1731107. Its molecular function is described by: protein binding; phosphatidylserine binding. It is involved in the biological process described with 13 unique terms, many of which group under: response to stress; regulation of synapse organization; anatomical structure regression; positive regulation of phagocytosis, engulfment; interspecies interaction between organisms. 39 alleles are reported. The phenotypes of these alleles manifest in: alimentary canal; adult head segment; hemocyte; adult peripheral nervous system; wing blade. The phenotypic classes of alleles include: behavior defective; phenotype; locomotor behavior defective; cell death defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late larval stages, during early pupal stages.
Coordinates
chr3L:1719923-1723705:-
Coord C1 exon
chr3L:1723580-1723705
Coord A exon
chr3L:1720170-1720384
Coord C2 exon
chr3L:1719923-1720169
Length
215 bp
Sequences
Splice sites
5' ss Seq
TAAGTTCGT
5' ss Score
-1.94
3' ss Seq
TCTCTCATGCACCCATGCAGTTC
3' ss Score
5.08
Exon sequences
Seq C1 exon
ATGGCTACATCGCGAGCGCAGGAGAATGCGTGCCGCATTGTTCGGAACCCTGCCAGCACGGTAGATGCATCTCCCCGGAGAAGTGCAAGTGTGATCATGGTTACGGAGGACCCGCCTGCGATATAA
Seq A exon
TTCACTCCGGCTCAGTTATACAGGTGCAAGCAGGCTATCGGTCACTAATCCCCACCACCAAAACGGGAGCTTCCGGGAGCGGAACTTCTTCCGGCTCCTGGGTTTCCCGTGGCTAGCAAGCGAAAGGCAAAAGCAAGAAAAAAGCAACTAACTGTCGAACCCGTACCTTGTGATCCGTAACCGCAGCTAACCATGTTTGTGTCACTCTTCGGTAG
Seq C2 exon
ATTGCCCACCCGGCTGGTATGGCCGGAACTGCTCGATGCAGTGCGACTGCCTGAACAACGCGGTATGTGAGCCCTTTTCAGGCGACTGCGAGTGCGCCAAGGGCTACACCGGAGCACGCTGCGCGGACATCTGTCCGGAGGGCTTTTTCGGGGCCAACTGCTCGGAGAAGTGCCGATGCGAGAACGGCGGCAAGTGTCACCACGTGTCCGGCGAATGCCAGTGTGCTCCCGGTTTCACGGGTCCCCT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0027594-11-6,11-5-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence inclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF075468=EMI=PD(8.5=14.0),PF0141414=DSL=PU(4.1=4.7)
A:
NA
C2:
PF0005319=Laminin_EGF=WD(100=56.6),PF126612=hEGF=PU(84.6=13.3)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0306204
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0072681, FBpp0306205
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTAGATGCATCTCCCCGGAG
R:
GTGAAACCGGGAGCACACTG
Band lengths:
305-520
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)