DmeALTD0000173-1/4 @ dm6
Alternative 5'ss
Gene
FBgn0261238 | Alh
Description
The gene Alhambra is referred to in FlyBase by the symbol DmelAlh (CG1070, FBgn0261238). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (13 unique). Gene sequence location is 3R:7094596..7124185. Its molecular function is described by: DNA-binding transcription factor activity. It is involved in the biological process described with: larval somatic muscle development; regulation of transcription, DNA-templated; haltere development; molting cycle, chitin-based cuticle; instar larval development. 88 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; wing; larva; embryonic/larval nervous system; RP2 motor neuron. The phenotypic classes of alleles include: phenotype; fertile; courtship behavior defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.
Coordinates
chr3R:7095580-7096820:-
Coord C1 exon
chr3R:7096516-7096820
Coord A exon
NA
Coord C2 exon
chr3R:7095580-7095843
Length
0 bp
Sequences
Splice sites
5' ss Seq
GAGGTGGGT
5' ss Score
7.07
3' ss Seq
CCTTGACTTTTTACTTTCAGTCC
3' ss Score
8.29
Exon sequences
Seq C1 exon
ACACGTGTCTGCAGCCCATGGATCCAACAATGCTGGGAACAGCAACAGCAGCGTTTGGAGCTTAACTGCCAGTAGCACCGTCAACAGCAACAGTTTGCATCACCAACATTCATCGCAGCAGCAGCAGCAGCATCAGGCGCAACACCAGTCGCATCCGTTGCAGCAACAGCAGCAGCAGCAGCAACAAGTGCAACATCATCTGCATCAGTCGCACCACACCAGCGCTGCTGTGGCAGCCGCTCATATGCTTGGCGTGGGAATGAGCCTGGGCGCTGGAGGTGGTGCTGCCGGTGGAATTGGACGAG
Seq A exon
NA
Seq C2 exon
TCCCAACTAAGGCGCGACGATAACCTCGCCAAAACTAGCTGAAAGTCGCACAGTGAGCAAGTCCTTCAGCAGCCGCAGCAACAGATAAAGTTAAAGAGAAAGCAGCAGTCACTGGCCAAACGAGGAGCCCGTCATAGCAGTACCAGTACCAGCAGCAGTAGCAGCAATCACGGCAGCAAAAAACTGCCCCAGCCCAGCAAATACAGCAAGCTAAGTGCGGCGGAGTCTAGCTTTCGGCAGCTGATCGACAAAAATGAAGATGAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261238-32-19,33-19,34-19,35-19-1/4
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence exclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.956 A=NA C2=0.993
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0306735
Main Skipping Isoform:
FBpp0303393
Other Inclusion Isoforms:
FBpp0306736
Other Skipping Isoforms:
FBpp0289721, FBpp0289722, FBpp0306737
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCATCTGCATCAGTCGCACC
R:
TACTGCTATGACGGGCTCCTC
Band lengths:
253-384
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)