Special

DmeALTD0000957-4/5 @ dm6

Alternative 5'ss

Gene
FBgn0033784 | CG13322
Description
The gene Squamous cell carcinoma-related oncogene 3 is referred to in FlyBase by the symbol DmelSCCRO3 (CG13322, FBgn0033784). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:12934234..12936535. Its molecular function is described by: ubiquitin-like protein binding; ubiquitin conjugating enzyme binding; cullin family protein binding. It is involved in the biological process described with: positive regulation of ubiquitin-protein transferase activity; negative regulation of cell growth; positive regulation of protein neddylation; protein neddylation; positive regulation of apoptotic process. 9 alleles are reported. The phenotypes of these alleles manifest in: eye; wing blade; macrochaeta. The phenotypic classes of alleles include: female semi-fertile; size defective; increased cell number; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr2R:12935779-12936425:-
Coord C1 exon
chr2R:12936325-12936425
Coord A exon
chr2R:12936311-12936324
Coord C2 exon
chr2R:12935779-12936260
Length
14 bp
Sequences
Splice sites
5' ss Seq
CGCGTGAGT
5' ss Score
8.4
3' ss Seq
AATAACAACAGCAATCGCAGTGA
3' ss Score
-7.01
Exon sequences
Seq C1 exon
GCGCTGGAGCACGGTGAACTGAAAATGTGAATGAAAACCATCAATAGAGAGAGACGAGCGCGATTTGGTGGCACCAAATGCTGCAGTTGCAACCTGCACAT
Seq A exon
GTATGTGTATACGC
Seq C2 exon
TGACAACAAAGAATCGGAATCGGAATCGTACTTGTTTGTACTCGCACAGGACGTACTTGGAATCGGAATCGGAATAGCCACTACCATATGCCAGAGGAGGGAATCGCAGTGCCAATGCATAGTTAATAAATTTCCCAGAAGCTATACGACCAGCAGACCTCAATTGCAATTGCACGCCCCTTGACAAATCACAGTGTCTCAGCCAAAACGAAACTGGAAGCCATCGAGTGCTCCCGTTAAGCAAGCAACTGCAGGCGGAGCACGGGGGAGGAGTAGGACCTGGTGGTGCACCAAGCACGCCCGCACTATGGGCAATTGCCTGAAATGCTTCCAGTCTGCCGCCGAACAATCGATGCCAACGAACGCCTCGTCCCCCAATTCACACAATTCCAATTCCAACGCCTGCCAGACGGCCACCAGCCTTGCAAATTGCTACGAATCGGTGGGCATTAATCCCAATGCCAACGAGCGCTGCGCCTTAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033784-0-1,1-1,2-1,3-1,4-1-4/5
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=0.305
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
NO


Main Inclusion Isoform:
NA


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGAGAGACGAGCGCGATTTG
R:
CGTCCTGTGCGAGTACAAACA
Band lengths:
108-122
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)