DmeALTD0003501-2/2 @ dm6
Alternative 5'ss
Gene
FBgn0036741 | CG7510
Description
The gene anchor is referred to in FlyBase by the symbol Dmelanchor (CG7510, FBgn0036741). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:17621824..17630971. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport; intracellular signal transduction. 9 alleles are reported. The phenotypes of these alleles manifest in: syncytium; cell; dorsal-ventral compartment boundary of imaginal disc; wing posterior compartment; wing disc posterior compartment. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality during development; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.
Coordinates
chr3L:17628279-17628799:+
Coord C1 exon
chr3L:17628279-17628347
Coord A exon
chr3L:17628348-17628371
Coord C2 exon
chr3L:17628427-17628799
Length
24 bp
Sequences
Splice sites
5' ss Seq
CGGGTAGGT
5' ss Score
8.53
3' ss Seq
TAATTTTTAAATTGCTACAGAAT
3' ss Score
5.51
Exon sequences
Seq C1 exon
TAACCGTTGGCTGTTTGGTGCTGCATCAGCGTTATAAGAAACGATACGAAAAGTACATGACCTATTCAC
Seq A exon
GTGAGTTGTCCAATCCGGAGTCGG
Seq C2 exon
AATCATCCGATCTGCACTCGACCATATCAACGACTAATCTATTGAGTCACACGGATCAATCGTCCATCAGGCAAAGCGTTCGCACAGCTTCTTATTCGTCTTCATCCGACGATGAGGAAATGATACCAACAGCTGCGGGACTGCCAACCAGTAGGTCAAATGGTGCTGCCAGTGGAGGAGCAGGATCAGGCGGAGGAGGTTGTGGTTCTGGCAATGGAACTTGCTGTTCGGGCGGCGCGCCTGTGAGCAATTCCTCAACAACCAGCACCGTGGTTGTGGACATTGAGGATCTGTTGAATCGCACACGCCAACGAGCCAGTGGTGCCAACAATAAAGATCTAAACAAGATCGAAAGTGCACCTGCCACGGAAGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0036741-10-9,11-9-2/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.621
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0305332
Main Skipping Isoform:
FBpp0074947
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAACCGTTGGCTGTTTGGTGC
R:
GTCGTTGATATGGTCGAGTGCA
Band lengths:
103-127
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)