DmeALTD0004702-1/3 @ dm6
Alternative 5'ss
Gene
FBgn0020445 | E23
Description
The gene Early gene at 23 is referred to in FlyBase by the symbol DmelE23 (CG3327, FBgn0020445). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:3334875..3354829. Its molecular function is described by: ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: regulation of circadian rhythm; transmembrane transport. 23 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: circadian rhythm defective; viable; locomotor rhythm defective; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during late larval stages.
Coordinates
chr2L:3337483-3338436:-
Coord C1 exon
chr2L:3338244-3338436
Coord A exon
NA
Coord C2 exon
chr2L:3337483-3337894
Length
0 bp
Sequences
Splice sites
5' ss Seq
GATGTGAGT
5' ss Score
7.77
3' ss Seq
TTCCATCCTCTCTGTTGTAGTCC
3' ss Score
9.01
Exon sequences
Seq C1 exon
TAACTCCCCAGCTTCCTTGTCTTACCACTTTGAGAAGTCTGCGGCGGCGAACCAACAGAAGCAGCATCACAACATAAACATCTGCAACAGCCACCACCCACATCACCACTCCCAGAATCAGCCCCAGCACAGTTTGCAGCTGACCTTCCAGAACCTGAACGTTTTGCACAACGAACGCCAAATACTTTCCGAT
Seq A exon
NA
Seq C2 exon
TCCCTGCGAGGTCCTGGCCATCATGGGTCCTTCGGGCAGCGGGAAGACCACTCTGCTGGACTGCCTCAGTGGTCAGCGGCACATTGACAGCGGCAGTGTGTTCCTCAACCGTGAGCCCCTGACCAAAAAGTGGCGTCGAAGGATCGGCTATGTCCTCCAGGAGGAGATCTTCTTCCCGCAATTGACGCTCCGCGAAACGGTGGTCTATACTGCGCTGCTGCGACTGCCGGAATCAATGCCGCGGGCGGAGAAGATGCGCCAGGTGGACCACATACTGGAGGCTCTGGAATTGGGTTGCTGTCAGCAGACCAAGTTCGGGGACTACCTCAACCGTGGACTCTCCGGTGGCGAGAAGAAGCGGGCGAATATCGCCTGTGAACTGCTGACCAATCCGCTGCTCATGCTCCTGGAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0020445-7-4,8-4,9-4-1/3
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence exclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.549 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0000522=ABC_tran=PU(5.3=11.3)
A:
NA
C2:
PF0000522=ABC_tran=FE(91.3=100)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0088917

Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0308631, FBpp0308632
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTGACCTTCCAGAACCTGA
R:
AGTCCAGCAGAGTGGTCTTCC
Band lengths:
118-135
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)