DmeALTD0005724-1/3 @ dm6
Alternative 5'ss
Gene
FBgn0015774 | NetB
Description
The gene Netrin-B is referred to in FlyBase by the symbol DmelNetB (CG10521, FBgn0015774). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (2 unique). Gene sequence location is X:14686038..14749376. Its molecular function is unknown. It is involved in the biological process described with 12 unique terms, many of which group under: cell recognition; tissue development; regulation of cell projection organization; synaptic target attraction; salivary gland boundary specification. 40 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; plasma membrane bounded cell projection; ventral nerve cord; appendage; optic nerve. The phenotypic classes of alleles include: partially lethal - majority die; phenotype; visible; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period.
Coordinates
chrX:14692306-14693195:-
Coord C1 exon
chrX:14693007-14693195
Coord A exon
NA
Coord C2 exon
chrX:14692306-14692455
Length
0 bp
Sequences
Splice sites
5' ss Seq
AGCGTGAGT
5' ss Score
8.2
3' ss Seq
ACATACCTCCCTCTTTACAGGTT
3' ss Score
10.55
Exon sequences
Seq C1 exon
TGTGCCAGTGCAACGGACACGCCCGTCGCTGCCGCTTCAATCTGGAGCTGTACAAACTATCTGGACGGGTTTCGGGAGGTGTATGCTACAACTGCCAGCACGATACTACCGGAAGATACTGCCACTATTGCCGCGAGGGATATTATCGGGATGCCACTAAGCCGCCAAATCATCGCAAAGTCTGCAAGC
Seq A exon
NA
Seq C2 exon
GTTGCGATTGCCATCCAGTGGGCTCGACGGGCAAGACGTGCAATCACCTGAGTGGCCAGTGTCCCTGCAAGGAGGGCGTCACCGGACTAACTTGCAACCGATGTGCCCGAGGCTATCAGCAGACCCGCTCCCACGTGGCACCCTGCATCA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0015774-6-7,7-7,8-7-1/3
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=WD(100=95.3)
A:
NA
C2:
PF0005319=Laminin_EGF=WD(100=94.1)
Main Inclusion Isoform:
FBpp0073757
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0291226, FBpp0291227, FBpp0291228, FBpp0293414, FBpp0293415, FBpp0303986
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCAGTGCAACGGACAC
R:
GATGCAGGGTGCCACGTG
Band lengths:
336-813
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)