DmeALTD0005787-4/4 @ dm6
Alternative 5'ss
Gene
FBgn0265011 | Np
Description
The gene Notopleural is referred to in FlyBase by the symbol DmelNp (CG34350, FBgn0265011). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:8992945..9006587. Its molecular function is described by: serine-type endopeptidase activity; serine-type peptidase activity. It is involved in the biological process described with: proteolysis; liquid clearance, open tracheal system. 56 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval integumentary system; posterior crossvein; late embryo; humeral bristle; crossvein. The phenotypic classes of alleles include: lethal - all die before end of larval stage; developmental rate defective; increased mortality; phenotype.
Coordinates
chr2R:9001384-9005376:-
Coord C1 exon
chr2R:9005249-9005376
Coord A exon
chr2R:9005004-9005248
Coord C2 exon
chr2R:9001384-9001606
Length
245 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGA
5' ss Score
7.69
3' ss Seq
CTTGTGAACTCTTTTTGCAGATG
3' ss Score
9.86
Exon sequences
Seq C1 exon
AGACGTGCGCAACTTGTCGCGCTCTTAACTTGGTCTTCTGCTCGTCTTCCGTCTTCCGCGACTGTGTGTGTGTGTGCGAGTGCGTCTGTACTCGGGGACTTAGCGAGTGTGCGTGTGTGTGTGCGAGT
Seq A exon
GTGAGTGAAATAATTGGCCTGACCCAAAGTCCCGAGGCAAGTTCAAGTGCAAGAATACAAGCCAAAACCAAAGCAACGAAATCCCAACCGGGAAAGGAAACGAATCTCGGGAAACAAATTTTCCCAGGCGGCTAACAGTGCTTTGTGTGATCTTTTTTTGAAAGAAGCGAAAGGTAGAACTGCGGAAAAAGGCCGAGAGCCAGTGTCAAAAGTGAAGAAACTCATAAAACGAACGAGCCACAAAC
Seq C2 exon
ATGGGTGCTCAACACACGGACACAGGCACCTATACGTACACAGCAGCCAGTAGGGCGGTAGAAGCCTCAGATCTGACACCCAAAAGAATTGGAGCACCAGCGATAGCCACTTCTAGAATGCCACTCACCAGCCTCGTCTTCAGCCTCCTCACGCTGGGCAGCCTGATGCTGTTGACGGCAGACGCCAGTCCCGTCTTCGTGGATAATCCCAGCTTAGCACAGT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0265011-2-2,3-2,4-2,5-2-4/4
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.013
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTTCTGCTCGTCTTCCGTCT
R:
TATCCACGAAGACGGGACTGG
Band lengths:
300-545
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)