DmeALTD0006130-2/2 @ dm6
Alternative 5'ss
Gene
FBgn0032358 | Ppt2
Description
The gene Palmitoyl-protein Thioesterase 2 is referred to in FlyBase by the symbol DmelPpt2 (CG4851, FBgn0032358). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:11280298..11281920. Its molecular function is described by: thiolester hydrolase activity; palmitoyl hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: macromolecule depalmitoylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages.
Coordinates
chr2L:11280821-11281406:+
Coord C1 exon
chr2L:11280821-11280928
Coord A exon
chr2L:11280929-11280932
Coord C2 exon
chr2L:11281133-11281406
Length
4 bp
Sequences
Splice sites
5' ss Seq
TAAGTGAGA
5' ss Score
2.17
3' ss Seq
TTTTTTGGTAATATTTTCAGCTA
3' ss Score
5.6
Exon sequences
Seq C1 exon
GATACTCACAAGGAGGCCTTTTGGCCCGGGCGGCCATCCAAAGTCTGCCCGAGCACAATGTGAAGACCTTTATATCTCTATCCTCGCCACAGGCGGGGCAATACGGCA
Seq A exon
GTAA
Seq C2 exon
CTAGCTTCTTGCATCTAATCTTTCCCGACTTGGCGGCCAAGACAGCCTTCGAATTGTTCTACTCGCGCGTGGGACAGCACACCTCGGTTGGTGGCTACTGGAACGATCCGCAGAGGCAGGATCTCTACCTGAAGTACAGCGAATTCCTGCCACTGATCAATAATGAGAAGAAGACCTCCAACTCCACATCTTTTAAGATGGGAATGGTGCGTCTAAATAAGTTGGTAATGATCGGCGGACCCAACGACGATGTGATTACTCCGTGGCAATCGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0032358-2-3,3-3-2/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence inclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0208910=Palm_thioest=FE(13.4=100)
A:
NA
C2:
PF0208910=Palm_thioest=FE(34.0=100)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0079801
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCTCTATCCTCGCCACAGGC
R:
CGCGCGAGTAGAACAATTCGA
Band lengths:
104-108
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)