Special

DmeALTD0008496-1/6 @ dm6

Alternative 5'ss

Gene
Description
The gene molting defective is referred to in FlyBase by the symbol Dmelmld (CG34100, FBgn0263490). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 3R:24585653..24623899. Its molecular function is described by: nucleic acid binding; zinc ion binding. It is involved in the biological process described with: ecdysone biosynthetic process; positive regulation of circadian sleep/wake cycle, sleep; long-term memory; determination of adult lifespan. 42 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; prothoracic gland; trichogen cell; ring gland. The phenotypic classes of alleles include: behavior defective; visible; increased mortality; phenotype.
Coordinates
chr3R:24589162-24591421:+
Coord C1 exon
chr3R:24589162-24589389
Coord A exon
NA
Coord C2 exon
chr3R:24590572-24591421
Length
0 bp
Sequences
Splice sites
5' ss Seq
AAAGTAACG
5' ss Score
2.88
3' ss Seq
GGCCCATTCTGGTTTTTTAGGTC
3' ss Score
9.39
Exon sequences
Seq C1 exon
TCAGTTCGATTCAAATTCCCAACGCGACGGTTACACCGCCCGATCCTCCCTCTCGAGGCTAATGAAATACTATTTGTTGGCGCTACAAATTGGCGGAGAATTCGAAATCTCATATCGTGTCGTTTCGCAAAAATAAAGATTTGTAAATCGTATCGCGTCGACGGGTCTTTTTTATTGGCGATTGTTTGTGATTGTGCCAAATAACGGCAATCAATGTTAATTGGAAAA
Seq A exon
NA
Seq C2 exon
GTCTACAACGTGGTCGACGAGTCGTGGTCAAAACGAAAGCAACGTCATTGTAAGAGAGAGAACAAATCGGCGAAAAAACCCTATAAACAAAACACAATTTCGTGGGTGTCTCGCATCGTGTGAGAACGAAAAGCTGGCGCTACAAATAATAAACTAAATTAATTAAACTAAGTAACTGCGAGAGAGCAACTAAAACAGAATGAGTGCCAACCGAAGAAGACGCAGTGCATCAGCTGCGAGTTCAATTGCAGCAGAAACAGCAACAGCAGCTACAGCAGCAACAGCAGAAGCGATATCAACTGCACCCTCCAAAGAGCAACTTTCTCCACCGATTGCTGGTGGCAGTGCTTCAGCTGATGAGGATTTACTGGAAATGCCTCGCATTTGCCGATGCTGTTGCAAACGGGATTTGAAATTACTCGGCTTATTCGAGGCCAGCCAACCAACACTGGCCAACACAACAGTGGCATCAGCATCAGCAGCAGCATCAGTGGCATCGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263490-1-1,2-1,3-1,4-1,5-1,6-1-1/6
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=0.659
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
PF0777610=zf-AD=PU(42.9=13.8)


Main Inclusion Isoform:
NA


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAAATCGTATCGCGTCGACGG
R:
TCGTTTTGACCACGACTCGTC
Band lengths:
121-156
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)