DmeALTD0008919-2/2 @ dm6
Alternative 5'ss
Gene
FBgn0261549 | rdgA
Description
The gene retinal degeneration A is referred to in FlyBase by the symbol Dmel
dgA (CG42667, FBgn0261549). It is a protein_coding_gene from Dmel. It has 12 annotated transcripts and 12 polypeptides (11 unique). Gene sequence location is X:8907068..9029476. Its molecular function is described by: diacylglycerol kinase activity; NAD+ kinase activity. It is involved in the biological process described with 14 unique terms, many of which group under: system process; nervous system process; multicellular organismal process; taxis; retina homeostasis. 67 alleles are reported. The phenotypes of these alleles manifest in: tergum; syncytium; plasma membrane bounded cell projection; Z disc; I band. The phenotypic classes of alleles include: flight defective; wild-type; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed during late pupal stages.
Coordinates
chrX:8999380-9002117:+
Coord C1 exon
chrX:8999380-9000240
Coord A exon
chrX:9000241-9000249
Coord C2 exon
chrX:9000682-9002117
Length
9 bp
Sequences
Splice sites
5' ss Seq
AAGGTGGAT
5' ss Score
3.2
3' ss Seq
CACACCATCACTTGTTGCAGGTG
3' ss Score
6.54
Exon sequences
Seq C1 exon
TAGTAGCTGCAACTGCAACATTCAGTCCAACGACGACAACAACAGCAGCAACAACAACAACAACAACCCAGATATCAACAGTGACAACAATATAACAACGATTACAACAGCAGCAAGAACAACAAGCATAGACAACAATCAATTGTCAGCAGCAACAACAACAACAGAGGCAAAAGGAGCATCAATACTAGCATCAAAACAGGCAGCAGCAACTTGCAACCACTTTGTAGCAACAACAACGCGAAATGCAGCAGCAGCAACAACCGTCCATCGACCAGCTGCCCGAGCCCACAGCTTCGACCAGCAATTCGGCCACAACTAAACCGACAATTGCAACAGCAACCACATCGACAACAACAACGTCTGGCAACAACTTCCACCAGCAACTGCAAGCAACAACGGCAGCCACCATGCAACGCCTGCGAACAACCTTTACGCGATCACGCACTCCAACAGGTGCCGAAATGAAGATGCAGAATAGCCTGGAGGTGCCCAAGCAG
Seq A exon
GTAAAAAAG
Seq C2 exon
GTGCGCTCCGCCTCTTTCGACGAGATGCAACTGGAGTCGCAGCGTGCCTCCTCCAGTCTGCTCAAGCAGCAATCCTCATCATCGGCCTCGGCAGACGAACGCTCCTCGGAGGCTGGCTTCCTGCAGGTTCCATTGGCGGCCCATCAGCAAAGATCCCATAGCTTCGATTCGGCAACTGCCTCGGCGGGCAGCGATGACTCGGGCACCTTTTTGGAGGTGCCACGACGGCTGAAGGCTCGACGCAGTTCGTCAACCAAGACACCGCCGCCTTGCATCCATTGTCACTATCTGGAGGAGTATGAGCGTCGTATGACCGCCGAACAGCGTTACTTCATCGATCATCGCGAGTTAACGGCTTTGAGCTACAGCAATACCAGCTCGGAGGCGAGTGAGGATGAGGATGAAGTTGAGGGCCATAACGCGGAGGAAGAGGAGGAGGGCAGTGCGGCCATCGAGGATGCCGAGGAGGAGACCACGGAGGCAGCTACCGAAGAAGCGGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261549-9-8,10-8-2/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.800
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0305779
Main Skipping Isoform:
FBpp0305778
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0291800, FBpp0291805, FBpp0310579, FBpp0310580
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCAACAGGTGCCGAAATGA
R:
CGACTCCAGTTGCATCTCGTC
Band lengths:
92-101
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)