Special

DmeALTD0009103-2/13 @ dm6

Alternative 5'ss

Gene
Description
The gene shibire is referred to in FlyBase by the symbol Dmelshi (CG18102, FBgn0003392). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (7 unique). Gene sequence location is X:15892116..15906716. Its molecular function is described by: GTP binding; actin binding; microtubule binding; GTPase activity. It is involved in the biological process described with 49 unique terms, many of which group under: mitotic cell cycle; synaptic signaling; organelle fission; cell motility; cell communication. 104 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; apical plasma membrane; pacemaker neuron; cell division site; neuromuscular junction. The phenotypic classes of alleles include: behavior defective; sensory perception defective; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chrX:15892200-15893150:+
Coord C1 exon
chrX:15892200-15892248
Coord A exon
chrX:15892249-15892251
Coord C2 exon
chrX:15892828-15893150
Length
3 bp
Sequences
Splice sites
5' ss Seq
GTTGTCAGT
5' ss Score
-1.59
3' ss Seq
GCAGCAATTGTATTTTGCAGAGG
3' ss Score
4.54
Exon sequences
Seq C1 exon
TTAGTCGAAAAAATCCATTGAAACGATTTGGAAGCGGAGTGTGGTGATA
Seq A exon
GTT
Seq C2 exon
AGGAGTGTGTGCAGTGAAGTAAAGCCAGCGATTAAAGGAAACAGCATAGAAAAAAAAAAGACCCGGGAGCTGAGCAGTAAAAACACAAACATCCGGACGAGTTGGGATCGCAGTTCGATCTGATCTGATCTGATATCTAATCTAATCTAATTGTGAGGGAAATCGGACCTCGCCGCAATGGATAGTTTAATTACAATTGTTAACAAGCTGCAAGATGCGTTCACATCGCTCGGCGTCCACATGCAACTGGATCTGCCGCAGATCGCGGTGGTCGGTGGCCAGTCAGCTGGCAAGAGTTCCGTTTTGGAGAACTTTGTGGGCAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0003392-1-2,2-2,3-2,4-2,5-2,6-2,7-2,8-2,9-2,10-2,11-2,12-2,13-2-2/13
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=0.000
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
PF0035018=Dynamin_N=PU(11.5=40.8)


Main Inclusion Isoform:
NA


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATTTGGAAGCGGAGTGTGGT
R:
TTTTTACTGCTCAGCTCCCGG
Band lengths:
108-111
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)