DmeALTD0009159-1/2 @ dm6
Alternative 5'ss
Gene
FBgn0035539 | slow
Description
The gene slowdown is referred to in FlyBase by the symbol Dmelslow (CG7447, FBgn0035539). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:4384442..4403181. Its molecular function is described by: calcium ion binding; signaling receptor binding. It is involved in the biological process described with: anatomical structure development; synaptic target recognition; muscle attachment. 10 alleles are reported. The phenotypes of these alleles manifest in: muscle attachment site; embryonic/larval somatic muscle; wing. The phenotypic classes of alleles include: flight defective; partially lethal - majority live; viable; locomotor rhythm defective; size defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.
Coordinates
chr3L:4384527-4391221:+
Coord C1 exon
chr3L:4384527-4384627
Coord A exon
NA
Coord C2 exon
chr3L:4390450-4391221
Length
0 bp
Sequences
Splice sites
5' ss Seq
ATAGTATGT
5' ss Score
4.41
3' ss Seq
TATATTTATTTCACTTGCAGTGC
3' ss Score
8.45
Exon sequences
Seq C1 exon
CAGCCAGTTCGCTCGGTTTTTGTGCCTGGCATACGGAAGCGGCTAACGCAGAATCCGGAAAATCACAAGAGCCGTATATATTTCACAAATATATATATATA
Seq A exon
NA
Seq C2 exon
TGCCATCGAGTGAATTAAGGTAGCGGGACGCCAGCATCAAAATGCCAGAAATGATTTACTCGAGCTCTTTCCTGCTGCTCTGTTGCACAATCCTGCTGCTGGGAACAGTACAGAATGCCGGTTCCAATAGCACCAGCCCTCATCCTCACCAGAATCAAACTCATCGCGGACATGGTCACAGTCATCGAACGCGTCATCAGGGCAACTATTTGGCCACCCATCAAAGGCAGCAGCGCAGACTGCAGTCGCTGAATCAAGCCAAATCGGATGTGGAGCTGCTGCCCGGGGTCACCATGCACGAGGTCACCAGATTACGACGGGTTCAGCCACATAATCCCTACAATAAAGTGCAGACACGACGCCTACACCAATCGCGAAACCCCACCGAATGGGATTACAATACTTACAACATCATGACCAACACGTTCGGTCCACCGCCACCGCCGATGCCGTTGTCACCGCGATATGGAAAGGGCGAGGATAATACCCAGGATGTTGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035539-0-0,1-0-1/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.881
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
PF075468=EMI=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGTTCGCTCGGTTTTTGTGC
R:
TGATGACGCGTTCGATGACTG
Band lengths:
296-556
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)