DmeEX0000200 @ dm6
Exon Skipping
Gene
FBgn0261788 | Ank2
Description
The gene Ankyrin 2 is referred to in FlyBase by the symbol DmelAnk2 (CG42734, FBgn0261788). It is a protein_coding_gene from Dmel. It has 21 annotated transcripts and 21 polypeptides (20 unique). Gene sequence location is 3L:7655389..7718395. Its molecular function is unknown. It is involved in the biological process described with 9 unique terms, many of which group under: nervous system process; system process; positive regulation of multicellular organismal process; regulation of trans-synaptic signaling; organelle organization. 41 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; cell junction; synapse; cell component; dendritic tree. The phenotypic classes of alleles include: stress response defective; increased mortality; phenotype; neuroanatomy defective.
Coordinates
chr3L:7700389-7704050:-
Coord C1 exon
chr3L:7703846-7704050
Coord A exon
chr3L:7702628-7702654
Coord C2 exon
chr3L:7700389-7700548
Length
27 bp
Sequences
Splice sites
3' ss Seq
GTTTTCTCAATCCATTGAAGGTG
3' ss Score
7.54
5' ss Seq
AAGGTAACT
5' ss Score
9.01
Exon sequences
Seq C1 exon
GCCCAACCGGTTGATCCCGATCTCACGGCGAAGCTTTTGGGTCGCGGCGTGGCCGTATCCCCAATTGTTACGGTCGAGCCGCGTCGCCGTAAATTCCACAAGGCCATCACCCTCAGCATGCCCGCCCCCAAGGCTCACAGCCAGGGTATGATTAACCAGTACTCGGGCAATACGCCCACCCTGCGTCTGCTATGCTCCATTACAG
Seq A exon
GTGTGTTTCGGAAAAGGTCTCTAAAAG
Seq C2 exon
GCGGACCATCTCGTGCTCAATGGGAAGATGTCACCGGTTCCACGCCCTTGACATTTGTCAATGACTGCGTCTCCTTTACGACCACAGTATCAGCTCGTTTCTGGCTGATGGATTGCCGCAACATTTCGGATGCCACCAAAATGGCAACTGAACTGTACAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261788-'17-15,'17-14,18-15
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.058 A=0.000 C2=0.021
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBtr0303112fB28
Main Skipping Isoform:
FBpp0292244
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0292230, FBpp0292231, FBpp0292232, FBpp0292233, FBpp0292234, FBpp0292236, FBpp0292237, FBpp0292240, FBpp0292241, FBpp0292242, FBpp0292243, FBpp0306185, FBpp0310628, FBpp0310629, FBpp0310630
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCGTCTGCTATGCTCCATT
R:
CTGTGGTCGTAAAGGAGACGC
Band lengths:
112-139
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)