DmeEX0000204 @ dm6
Exon Skipping
Gene
FBgn0261788 | Ank2
Description
The gene Ankyrin 2 is referred to in FlyBase by the symbol DmelAnk2 (CG42734, FBgn0261788). It is a protein_coding_gene from Dmel. It has 21 annotated transcripts and 21 polypeptides (20 unique). Gene sequence location is 3L:7655389..7718395. Its molecular function is unknown. It is involved in the biological process described with 9 unique terms, many of which group under: nervous system process; system process; positive regulation of multicellular organismal process; regulation of trans-synaptic signaling; organelle organization. 41 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; cell junction; synapse; cell component; dendritic tree. The phenotypic classes of alleles include: stress response defective; increased mortality; phenotype; neuroanatomy defective.
Coordinates
chr3L:7706461-7708816:-
Coord C1 exon
chr3L:7707889-7708816
Coord A exon
chr3L:7707628-7707720
Coord C2 exon
chr3L:7706461-7706743
Length
93 bp
Sequences
Splice sites
3' ss Seq
CTTTCATATGTGTGTGTCAGGTG
3' ss Score
9.06
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
CGTCAATCATCCGGCTAAGAATGGTCTAACTCCCATGCATCTGTGTGCCCAGGAGGATAATGTGAATGTGGCTGAGATTCTGGAGAAGAACGGCGCCAATATCGACATGGCCACCAAGGCAGGCTACACTCCTTTGCATGTGGCCTCACATTTTGGGCAGGCCAACATGGTGCGTTTCTTGCTGCAGAATGGCGCCAATGTGGATGCGGCCACCTCAATTGGCTATACTCCGCTCCATCAGACCGCCCAGCAGGGTCATTGTCATATTGTGAATCTCCTGCTGGAGCACAAGGCTAATGCCAACGCTCAGACGGTCAATGGACAGACGCCTTTGCACATTGCCCGCAAACTGGGCTACATAAGTGTCCTAGACTCGTTGAAAACCATCACCAAGGAGGACGAAACAGCTGCTGCTCCTTCCCAAGCCGAGGAGAAGTATCGCGTGGTGGCTCCCGAGGCCATGCACGAATCCTTCATGTCCGACTCCGAGGAAGAGGGCG
Seq A exon
GTGACACTAACTGGCAACTGGACGCTGGCTACGAGTACGGCTTCGGGCCAATCTATCTGCCGTACTACCAGGGCGACAAGCACTATGTCTCCA
Seq C2 exon
GCGAAGACAATATGCTATCAGATCAACCATACCGCTATTTGACCGTTGATGAAATGAAATCCCTAGGCGACGACTCGCTGCCCATCGATGTGACCCGTGATGAGCGCATGGACTCCAACCGGATGACCCAGAGCGCCGAGTATGCCTCTGGTGTTCCGCCCACCATTGGGGAGGAGGTGATCAGTCCCCACAAGACCCAAGTCTACGGCAGTTCACCCAAGGCCACCGTGGATGGAGTGTACATTGCCAATGGATCTGGTCACGATGAGCCGCCGCATGTGGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261788_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.243 A=0.250 C2=0.714
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(16.7=4.8),PF0002325=Ank=WD(100=10.6),PF0002325=Ank=WD(100=10.6),PF127962=Ank_2=WD(100=22.6),PF0002325=Ank=WD(100=10.6),PF127962=Ank_2=WD(100=28.1)
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0292234
Main Skipping Isoform:
FBpp0292244
Other Inclusion Isoforms:
FBpp0292231, FBpp0292240, FBpp0292243
Other Skipping Isoforms:
FBpp0292230, FBpp0292232, FBpp0292233, FBpp0292236, FBpp0292237, FBpp0292238, FBpp0292241, FBpp0292242, FBpp0306185, FBpp0306186, FBpp0310628, FBpp0310629, FBpp0310630
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGCCGAGGAGAAGTATCGC
R:
CATCACGGGTCACATCGATGG
Band lengths:
181-274
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)