DmeEX0000431 @ dm6
Exon Skipping
Gene
FBgn0032797 | CG10186
Description
The gene Hig-anchoring scaffold protein is referred to in FlyBase by the symbol DmelHasp (CG10186, FBgn0032797). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 2L:19508953..19517204. Its molecular function is described by: peptidase inhibitor activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived; pain response defective; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.
Coordinates
chr2L:19515734-19517204:-
Coord C1 exon
chr2L:19517128-19517204
Coord A exon
chr2L:19516441-19516858
Coord C2 exon
chr2L:19515734-19516033
Length
418 bp
Sequences
Splice sites
3' ss Seq
ATGATATCTTTATATTCAAGTTT
3' ss Score
4.88
5' ss Seq
AAGGTCAAT
5' ss Score
3.77
Exon sequences
Seq C1 exon
GCTATGTTAAGTAAGGGATTGTAAATGTAAAGTTGAAGAAGACGGTGGATTTTAGAGAAACTAAGGAAACATATCGT
Seq A exon
TTTGGATCCAACAAGCGAGCTAGGATGCAAGAACCTTTCGCATTTGCTCGAATTTTCACCGAAACCTATCTTCACCGTTAAAGGGACCAACCACCGCCGAAAGCTGTCAAGTTGGGCGCTTCTCGCCCGATCTGTCAAAAGGCCAGAGCCAAAAAGGGGAGAAAGCAGCTGGCGTGGCTGCATTTCGTTTCCTTGGCTCGAAGTGAGAAGTTTCGGGCCACCGAGCTTGTCGAAAAAGTTACCAATTAAATTGGCCAGCAGAGGAATTTTGCAAGTTAGCTAAAATGCTATAAATCCGAGGCCAGTTCGGCGAAAGGAAAAAAATCAAAAAGGACACGGATACCCCGCAACTACAACGGAATCAAAATGAATCGCCTGCTGCTGCAGTGTCTAGTGACCACCATTCTGGTCTACAAAG
Seq C2 exon
TGATTTCGGTGCCGACCAGCACGATGAGCACCAGCATCCAGACGACCTCGGAGATTCCGCAGCAGGATGACGACGACGACGACTGGGAGGAGGACGACGACTCTCTGGAGTCTGACGACGATGGCCGCGTCTACAAGAATCCTCGCAACTCACCCTCCACCGAGTGTCCACGCGACGAGGAGCAGGCCACGCTGCTCGGCCAGAAGTGCTTGAGGAAGTGCTCCTCCGACGAGGATTGCAAGAGCAAGAAGAAGAAGTGCCTGTGCGACGGCGTCTGTGGCAATTCCTGCATTAAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0032797-'0-4,'0-0,1-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.495
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF0009516=WAP=WD(100=47.5)
Main Inclusion Isoform:
FBpp0080818
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0080819, FBpp0288794, FBpp0291317, FBpp0291318
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTAAAGTTGAAGAAGACGGTGGA
R:
CAGGAATTGCCACAGACGCC
Band lengths:
342-760
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)