DmeEX0001599 @ dm6
Exon Skipping
Gene
FBgn0051612 | CG31612
Description
This gene is referred to in FlyBase by the symbol DmelCG31612 (FBgn0051612). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:21762314..21795447. Its molecular function is described by: sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: positive regulation of nuclear cell cycle DNA replication; regulation of transcription by RNA polymerase II. 15 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages.
Coordinates
chr2L:21762314-21766160:-
Coord C1 exon
chr2L:21765963-21766160
Coord A exon
chr2L:21763572-21763726
Coord C2 exon
chr2L:21762314-21762899
Length
155 bp
Sequences
Splice sites
3' ss Seq
ACAGATTCCGATTCCAGCAGCCC
3' ss Score
1.48
5' ss Seq
AAGGTGCGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
GTATTCCCTTAAACTTCATGAGATTAGCCACTCGAAGGCAGTTGAGCGCAATTATCTCTGCCATTTTGCGGACTGCTCATATGCAGGGCGAACCCCGGAAAGCCTGAAAACCCACTTGGTCTCCCACTCCCAGGAAAATCACAAATGTGCGCGGATTAACTGCAGCTATGTGGGAAAGAGCGAGCTGCACCTAAAAAG
Seq A exon
CCCGGGCCCACAAAAAACATTGGCAATTAATTGTGAGTCCTTGGTTTGGACAGTAGCTGATAAGTGGAGTGGACATCCAACACACACATATGCAAGGATGCTCCCTTAGTGGGCTTCTGGGGAAACAGCTACAGAAGTATTGGGCATAATTGAAG
Seq C2 exon
GCACCTCAAGTCGGCTCATTCCACGGAGAAGAATGGTGAGGAGTGGTTTTCGTGCGATCAATGCGATTTCAGAGCCCGCATCAAGGGTCACCTCCGTCGGCACTCGTTGCGCCACTCGGGCCAGAAGCCCCACCAATGCCCCCACTGCGACTTCCAGTGCAGCACCATAGATAACCTACGTAAGCACATCATCAAGACGGGAAAGCATCCCGGCATGTTCATTTACCACTGCGCTAAGTGCTCCGATGAAGAAGCCGGTGAAATATTTAAGAGCAACAGCTACAAAGAATACCAGCACCACTTGAAGACTCACAAGGCTGGCTGAGAAAATATTTTAGGGAACGCTGTTTAAATTTAAATAATAATAGATTTTATCAACATCCTAATATCCTTTCATTAAACTAAAACATGAATTGATATTAATTCTAAAATATTCGTTTGAATACAGAACTGTTAAAGAAACATACAGAAAGAGATTAATTTATGCATGTTGGAAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0051612_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.050 A=0.000 C2=0.157
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF134651=zf-H2C2_2=WD(100=23.9)
Main Inclusion Isoform:
FBtr0085908fB202
Main Skipping Isoform:
FBpp0085262
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0290221
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTATGTGGGAAAGAGCGAGC
R:
ATGAACATGCCGGGATGCTTT
Band lengths:
256-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)