Special

DmeEX0001889 @ dm6

Exon Skipping

Gene
FBgn0053178 | CG33178
Description
This gene is referred to in FlyBase by the symbol DmelCG33178 (FBgn0053178). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:15082827..15084017. Its molecular function is described by: glutathione peroxidase activity; glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.
Coordinates
chrX:15082827-15083336:+
Coord C1 exon
chrX:15082827-15083041
Coord A exon
chrX:15083121-15083156
Coord C2 exon
chrX:15083257-15083336
Length
36 bp
Sequences
Splice sites
3' ss Seq
TTCCACCATTCAATTCACAGCTG
3' ss Score
7.93
5' ss Seq
AGGGTAATA
5' ss Score
5.47
Exon sequences
Seq C1 exon
CATTTGTCGAAGTCGGCTCAAAGCGAACGCACACACATTCCGCATCCGCCATGTCGGCCGCAGCTAGTAATTCCAGCAAGATGATGACATCGCCCGGCGATATGTTTACCCTGGAGAATCCTGTCTTTTGCTGCTATCTTTTTTGGTCCACAGTCCTGGTGGTGAAGATGCTGCTCATGTCGCTGCTAACGGCCGTTCAGCGTTTCCGGTATAAG
Seq A exon
CTGCTGGCGATCGTACCGTTGGCACTGCGGCGCAGG
Seq C2 exon
ATCTTTCCCAACCAGGAGGATCTGTTCTTCAAGAATCTTGAAGTGCAATTCGATGATCCGCATGTGGAGCGGGTCAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0053178_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (No Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0112413=MAPEG=PU(19.8=47.3)
A:
PF0112413=MAPEG=FE(7.7=100)
C2:
PF0112413=MAPEG=FE(19.8=100)


Main Inclusion Isoform:
FBpp0309372


Main Skipping Isoform:
FBpp0073780


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
FBpp0311919
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCTGGTGGTGAAGATGCTG
R:
TGCGGATCATCGAATTGCACT
Band lengths:
125-161
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)