DmeEX0002442 @ dm6
Exon Skipping
Gene
FBgn0261570 | CG42684
Description
The gene raskol is referred to in FlyBase by the symbol Dmel
askol (CG42684, FBgn0261570). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is X:17710144..17752007. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of Ras protein signal transduction; regulation of GTPase activity. 37 alleles are reported. The phenotypes of these alleles manifest in: border follicle cell; filamentous actin. The phenotypic classes of alleles include: cell adhesion defective; viable; behavior defective; smell perception defective; fertile; cell migration defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages.
Coordinates
chrX:17720587-17721615:+
Coord C1 exon
chrX:17720587-17720699
Coord A exon
chrX:17720948-17720974
Coord C2 exon
chrX:17721423-17721615
Length
27 bp
Sequences
Splice sites
3' ss Seq
ATCGTTCTACTAACCTGTAGATA
3' ss Score
6.9
5' ss Seq
GAGGTGGGT
5' ss Score
7.07
Exon sequences
Seq C1 exon
AAACCGAGGGAGAACTAACTCGCCTGATCAAGACGCTTCCCTGGGGTCCTTTATACTGCGTGCTGCAACAGGACGATCAGACATTCACCGCCTACTGCAGCGAGGAGATTTCG
Seq A exon
ATATTCCCGGCCACGCCCAAAAAGGAG
Seq C2 exon
CTAGGCGATGTTTGCTACGAGGACATTCCAAGGGTTCGGTTGGACCGAGTTCGTCGTCCTGCGAAGGCTTTGTGGGACGGACCGCCGACGTTGGTCGAGGAAAACGAGGATTCAGATTCGTGTGTTGGGGGCAGCGGCGGCATGAGTGGCATCAACGACATCGTCCTGAATACGACGCTCTACAGTGAACTAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261570_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.233
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0291977
Main Skipping Isoform:
FBpp0291975
Other Inclusion Isoforms:
FBpp0309494
Other Skipping Isoforms:
FBpp0291974, FBpp0309495
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGGTCCTTTATACTGCGTGC
R:
CCAACCGAACCCTTGGAATGT
Band lengths:
114-141
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)