DmeEX0003375 @ dm6
Exon Skipping
Gene
FBgn0036451 | CG9425
Description
The gene Helicase with zinc finger is referred to in FlyBase by the symbol DmelHelz (CG9425, FBgn0036451). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:14789935..14801089. Its molecular function is described by: RNA binding; metal ion binding. It is involved in the biological process described with: posttranscriptional gene silencing by RNA. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr3L:14789935-14791960:+
Coord C1 exon
chr3L:14789935-14790072
Coord A exon
chr3L:14791270-14791550
Coord C2 exon
chr3L:14791871-14791960
Length
281 bp
Sequences
Splice sites
3' ss Seq
ATATACATATATATTCTTAGTTG
3' ss Score
3.68
5' ss Seq
ACGGTAATT
5' ss Score
7.31
Exon sequences
Seq C1 exon
CGCGAATTTTCCCTCATACATACATAACTTATTTTTAACATTTTTCGACGTGATGTGCATTTTCTCTCATAGTTTTGTGCTTAACCATGTAAAATAGAATTAGTCCGTAGTGTACAAACAATAGGATTTAGTGCAAAG
Seq A exon
TTGCAGGCGCACTCTATAAATCCGTCTGTATATTTGTACTAAGTACACACAATTGTTTGGGAACCGATAAGAAGCGAGATATAAACAATTTCTGTTTTGGATTTAGCGAACATTACTGGCAGTCAACGAAGATGATTTAATCAATTCTTCAATATCCAAATAATTATCCGTACAAACAAGCCGGTCTTTAAAGTAATCTAAAATGTGAAATCGCCAATAGGAAAATTCAGGACTAGAATACTTAAGATGTGAAATTGTGTGCAAATTTCAAGAACACAACG
Seq C2 exon
TAAACATAATGCCCGCAAAGTATCTAAAACATTAATGTAAAAACGATAATCGATTTCTTATTATTAACCACACAAAAACTGTTAAATTGT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0036451_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=NA
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NA
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCGAATTTTCCCTCATACATACA
R:
ACAATTTAACAGTTTTTGTGTGGTT
Band lengths:
228-509
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)