DmeEX0004164 @ dm6
Exon Skipping
Gene
FBgn0263219 | Dscam4
Description
The gene Down syndrome cell adhesion molecule 4 is referred to in FlyBase by the symbol DmelDscam4 (CG42330, FBgn0263219). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 3L:8238647..8282398. Its molecular function is described by: cell-cell adhesion mediator activity; identical protein binding. It is involved in the biological process described with: homophilic cell adhesion via plasma membrane adhesion molecules; axon guidance; cell adhesion; dendrite self-avoidance. 17 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
Coordinates
chr3L:8273176-8275667:+
Coord C1 exon
chr3L:8273176-8273329
Coord A exon
chr3L:8274552-8274669
Coord C2 exon
chr3L:8275505-8275667
Length
118 bp
Sequences
Splice sites
3' ss Seq
CACACGACACACACACACAGCTA
3' ss Score
-0.25
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
Exon sequences
Seq C1 exon
TGCCCGCCCACTTTCAGACGAAGACCAAACAGATTTCGGTGGCCAAAGGAAAGCAGGTCCATGTGCAGTGCAACGTGCAGGGCGACAATCCCATCGACTTTAAATGGAAAATCCAGGCAACGCAACAGTATCTCGACGAGTCGCTGGATTCCCG
Seq A exon
CTACACAATAAGAGATCAAGTGCTCGACGACGGCATGGTCTCCGAATTGGGCATTTCGCACACATATCGCCAGGATACGGGCATTTATATCTGTCAGGCGAGCAATGCATTCGGACAG
Seq C2 exon
GACGAGATGTCCATTCAGCTCATCGTGCAGGAAGTGCCCGAGCAGCCGAAGAACCTTCGCATCAACTCGCAACAGTCGCGCAGCCTTCAGCTCACGTGGAGCCAACCCTTTGCCGGAAATAGTCCCATCGAGGAGTACCACATCTACTACAAACAAATATCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263219_MULTIEX1-2/8=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.080
Domain overlap (PFAM):
C1:
PF0767911=I-set=PU(50.0=94.2)
A:
PF0767911=I-set=FE(39.8=100)
C2:
PF0767911=I-set=PD(8.2=14.5),PF0004116=fn3=PU(44.6=74.5)
Main Inclusion Isoform:
FBpp0305766
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0289117, FBpp0289118, FBpp0289119, FBpp0305767
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAAGCAGGTCCATGTGCAGT
R:
TGTGGTACTCCTCGATGGGAC
Band lengths:
248-366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)