DmeEX0004322 @ dm6
Exon Skipping
Gene
FBgn0262740 | Evi5
Description
The gene Ecotropic viral integration site 5 is referred to in FlyBase by the symbol DmelEvi5 (CG11727, FBgn0262740). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is X:11430523..11454386. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: regulation of cell migration; regulation of GTPase activity; intracellular protein transport; regulation of protein localization; activation of GTPase activity. 12 alleles are reported. The phenotype of these alleles manifest in: border follicle cell. The phenotypic classes of alleles include: viable; fertile; cell migration defective.
Coordinates
chrX:11435729-11437137:-
Coord C1 exon
chrX:11437023-11437137
Coord A exon
chrX:11436775-11436792
Coord C2 exon
chrX:11435729-11436396
Length
18 bp
Sequences
Splice sites
3' ss Seq
AATTCTAAAATCACATACAGAAC
3' ss Score
2.81
5' ss Seq
AGCGTAAGT
5' ss Score
10.07
Exon sequences
Seq C1 exon
CTATGCCATTCAGACGGAGCTAATGCAGCTGCGCCGATCATACTTGGAGGTCTCGCATCAGCTGGAAAACGCCAACGAGGAGGTGCGCGGCCTGAGTCTACGGCTGCAGGAGAAT
Seq A exon
AACGTATCCATCGACAGC
Seq C2 exon
AATAACTCCCGGCAATCGTCCATTGACGAGCTCTGCATGAAGGAGGAGGCGCTGAAGCAGCGCGACGAGATGGTCTCCTGTTTGCTGGAGGAACTGGTGAAGGTGCGTCAGGGACTGGCCGAAAGCGAGGATCAGATCAGGAACCTCAAGGCCAAGGTCGAGGAGCTGGAGGAGGATAAGAAGACGCTGCGGGAAACGACGCCAGACAATTCGGTGGCTCATCTGCAGGATGAACTGATTGCTAGTAAACTTCGCGAGGCTGAGGCCTCACTTTCGCTAAAGGATCTCAAGCAGAGGGTGCAGGAGCTGAGCAGCCAGTGGCAGCGTCAATTGGCCGAGAATCAGCGCAGCGAAAGCGAACGCACCACCAACGCTGTGGACTCTACGCCCAAAAAGCTGTTGACCAACTTCTTTGACAGCTCCAAGAGTAGCGAGCACACGCAGAAGCTCGAGGAGGAGCTGATGACCACGCGCATACGCGAGATGGAGACGCTTACCGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0262740_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.167 A=1.000 C2=0.605
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF123293=TMF_DNA_bd=WD(100=26.9)
Main Inclusion Isoform:
FBpp0073392
Main Skipping Isoform:
FBpp0289957
Other Inclusion Isoforms:
FBpp0073391
Other Skipping Isoforms:
FBpp0289956, FBpp0304866
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTCTACGGCTGCAGGAGAAT
R:
CCAGTTCCTCCAGCAAACAGG
Band lengths:
118-136
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)