DmeEX0004837 @ dm6
Exon Skipping
Gene
FBgn0010051 | Itp-r83A
Description
The gene Inositol 1,4,5,-trisphosphate receptor is referred to in FlyBase by the symbol DmelItpr (CG1063, FBgn0010051). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:5517117..5539411. Its molecular function is described by: calcium ion binding; phosphatidylinositol binding; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; inositol 1,4,5 trisphosphate binding. It is involved in the biological process described with 22 unique terms, many of which group under: behavior; response to nutrient levels; response to starvation; sensory perception; regulation of feeding behavior. 52 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; alimentary canal; cellular anatomical entity; developing material anatomical entity; organelle. The phenotypic classes of alleles include: phenotype; increased mortality; size defective; body size defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages.
Coordinates
chr3R:5531202-5532306:+
Coord C1 exon
chr3R:5531202-5531343
Coord A exon
chr3R:5531414-5531440
Coord C2 exon
chr3R:5531660-5532306
Length
27 bp
Sequences
Splice sites
3' ss Seq
CAATGTTTTCTCTTAACAAGCTG
3' ss Score
3.52
5' ss Seq
AGGGTAAGA
5' ss Score
9.21
Exon sequences
Seq C1 exon
GTGGTTAAACTCGCAAGGGACCTGATTTATTTCGGATTCTACAGCTTTAGCGATCTTCTAAGACTTACGAAGACGCTTCTGTCCATCCTGGACTGCGTGTCCGATACTTCATCAGGTGAATTTGCCAGCACGGATATTGATT
Seq A exon
CTGTCGAAGAGGAGACTAACGCAGAGG
Seq C2 exon
CCGAAGGTGGAGTTCTACGCTCGATTGGGGACATAAATACAGTAATGACATCTTTGGCCCTGGGATCAGTGGGCCAGGCTATAGCTGCGCCCACGATCTCCCTGCAGCAGCGGAAGTCCGTCTCCCAACTAATGAAGGAGTATCCCTTGGTGATGGACACGAAACTGAAAATAATCGAGATACTGCAGTTCATTTTGGACGTTCGTCTGGACTATAGGATCAGCTGTCTGCTCTCCATATTCAAGCGGGAGTTCGACGAGTCCGAGGTGGCCGCTTCGGCCGCTAGCAATGAGGCAAGTCAGCAGCAGTCGCAACAACAGGAACCGCAGACGCCTGGCAGCTCCAATGAGACTGATCCCCTCGACAGTGCCGAGTCTGTGGCCGCCGGCGCTGCCGCAGCCGCCGCTACCACTGCGCGGCAGAAGAACATCGACCTGGAGTCCATCGGCGTGCAGGCGGAGGGAATCTTCGACTGCGAGCGGAGCGACGCAGCTAACCTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0010051_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=0.000 C2=0.153
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0078336
Main Skipping Isoform:
FBpp0078335
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0310670
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAGGTGAATTTGCCAGCACG
R:
TATAGCCTGGCCCACTGATCC
Band lengths:
114-141
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)