DmeEX0006379 @ dm6
Exon Skipping
Gene
FBgn0067861 | Sdic1
Description
The gene Sperm-specific dynein intermediate chain 1 is referred to in FlyBase by the symbol DmelSdic1 (CG9580, FBgn0067861). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:20174217..20178638. Its molecular function is described by: dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: positive regulation of ATP-dependent microtubule motor activity, plus-end-directed; microtubule-based movement. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed in adult male stages.
Coordinates
chrX:20176238-20178397:-
Coord C1 exon
chrX:20178270-20178397
Coord A exon
chrX:20177819-20177851
Coord C2 exon
chrX:20176238-20176414
Length
33 bp
Sequences
Splice sites
3' ss Seq
CCACTCCTCGCCTCTGTCAGGAT
3' ss Score
6.74
5' ss Seq
AAGGTACTA
5' ss Score
7.52
Exon sequences
Seq C1 exon
CGGCGGAAAGAAACAGCCTCTCAACCTAAGCGTCTACAATGTGCAGGCTACGAACATTCCACCAAAAGAGACACTGGTCTACACAAAGCAGACCCAGACGACCAGTACCGGAGGCGGAAACGGCGATG
Seq A exon
GATATATGGAGGACTGGTGGCGTCCACGTAAAG
Seq C2 exon
TGCTTGCATTTGATGCCCAAGGAGACGACGAAGAGAGCTCACTGCAGAACCTGGGCAACGGATTCACCTCCAAGCTGCCACCGGGCTATCTCACCCACGGCCTGCCCACCGTTAAGGACGTCGCCCCGGCCATCACACCACTCGAGATCAAGAAGGAGACTGAAGTGAAGAAGGAGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0067861_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.534 A=0.833 C2=0.379
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=WD(100=75.0)
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0301958
Main Skipping Isoform:
FBpp0088559
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCAGGCTACGAACATTCCAC
R:
GAGCTCTCTTCGTCGTCTCCT
Band lengths:
127-160
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)