Special

DmeEX0007148 @ dm6

Exon Skipping

Gene
FBgn0028646 | aralar1
Description
The gene aralar1 is referred to in FlyBase by the symbol Dmelaralar1 (CG2139, FBgn0028646). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 3R:30445635..30455867. Its molecular function is described by: L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; transmembrane transporter activity; identical protein binding; calcium ion binding. It is involved in the biological process described with 6 unique terms, many of which group under: transport; ion transmembrane transport; dicarboxylic acid transport; amino acid transport; localization. 17 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages.
Coordinates
chr3R:30447412-30448569:-
Coord C1 exon
chr3R:30448346-30448569
Coord A exon
chr3R:30447753-30447788
Coord C2 exon
chr3R:30447412-30447578
Length
36 bp
Sequences
Splice sites
3' ss Seq
CGCAATTCTCACTCTCAAAGCTG
3' ss Score
4.81
5' ss Seq
TAGGCAAGT
5' ss Score
1.91
Exon sequences
Seq C1 exon
GTAACTGAGGGTCACAAAGTGAGCTTCCCGTATTTCATCGCATTTACCTCGCTGCTGAACAACATGGAACTGATCAAACAAGTCTACCTGCACGCCACCGAGGGCAGTCGCACGGATATGATCACCAAGGATCAGATCCTCCTCGCCGCCCAAACGATGAGCCAAATCACGCCGCTGGAGATCGACATACTTTTCCACCTGGCGGGCGCCGTCCATCAAGCAGG
Seq A exon
CTGGTGGAAGCGCAGGAGAAAGATACCTCCGAGTAG
Seq C2 exon
CCGCATCGACTATAGTGACCTGAGCAACATCGCACCCGAGCATTACACCAAGCATATGACACATCGTCTGGCGGAGATCAAGGCGGTGGAGAGTCCTGCGGACCGATCTGCCTTTATTCAGGTCCTGGAGAGCTCTTACCGTTTCACTCTCGGTTCCTTTGCCGGCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0028646_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (No Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
NO
A:
NO
C2:
PF0015322=Mito_carr=PU(15.3=26.3)


Main Inclusion Isoform:
FBpp0297541


Main Skipping Isoform:
FBpp0085054


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
FBpp0085055, FBpp0085056, FBpp0085057, FBpp0303322
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCAAACGATGAGCCAAATC
R:
TAATGCTCGGGTGCGATGTTG
Band lengths:
122-158
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)