DmeEX0008303 @ dm6
Exon Skipping
Gene
FBgn0031016 | kek5
Description
The gene kekkon 5 is referred to in FlyBase by the symbol Dmelkek5 (CG12199, FBgn0031016). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:19353181..19471914. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of BMP signaling pathway. 39 alleles are reported. The phenotypes of these alleles manifest in: bristle of mesothoracic tergum; sensory system; adult mesothoracic sensillum; scutellar bristle; non-connected functional system. The phenotypic classes of alleles include: viable; size defective; visible; short lived; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 06-12 hour embryonic stages.
Coordinates
chrX:19362967-19433272:+
Coord C1 exon
chrX:19362967-19363021
Coord A exon
chrX:19379213-19379280
Coord C2 exon
chrX:19433154-19433272
Length
68 bp
Sequences
Splice sites
3' ss Seq
ATTATTTTTTTTTTTTTTAGTTG
3' ss Score
8.84
5' ss Seq
ACGGTAAGA
5' ss Score
10.65
Exon sequences
Seq C1 exon
ACTATACCTGTAGCATTGTTCAAACGCAAATGATTGGCGTCAAATAATGAAAAAG
Seq A exon
TTGAAGTGCTTCAAGCTTATCTATTCTCCCAGCTACTTTGTGTGACAATTAGCAGTTCCCAGTGGACG
Seq C2 exon
GGTGTCGTCCTCGTTAGGCAATCGTCATGGTCCTTCAAGGCAAGAACATAAATATTGAAACAAATCGGAGCATTGAACAAAGCACAGGACGAAGGAACTAATTGCACAAAACAAGCCTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0031016_MULTIEX1-1/2=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=NA
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NA
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGTAGCATTGTTCAAACGCA
R:
AGGCTTGTTTTGTGCAATTAGTTCC
Band lengths:
167-235
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)