DmeEX0008936 @ dm6
Exon Skipping
Gene
FBgn0259175 | ome
Description
The gene omega is referred to in FlyBase by the symbol Dmelome (CG42280, FBgn0259175). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3L:14672839..14747868. Its molecular function is described by: serine-type peptidase activity; dipeptidyl-peptidase activity. It is involved in the biological process described with: proteolysis. 30 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; male semi-sterile; fertile; developmental rate defective; small body. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages.
Coordinates
chr3L:14680199-14744443:+
Coord C1 exon
chr3L:14680199-14680787
Coord A exon
chr3L:14739435-14740148
Coord C2 exon
chr3L:14744189-14744443
Length
714 bp
Sequences
Splice sites
3' ss Seq
AAAAACAAAAAAACAACAAGTTT
3' ss Score
-7.13
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
Exon sequences
Seq C1 exon
CCCTGACATGCAAGCCAGAGTTTGAAATCCGTGACGACAATCATTGCATCATCGCGATTAGAAGGCATTATTGGGAGTAGCCAAGCAAGATGAGTGCTGCCGGCTGGCTTGATATGAATGCAGCTCTTCAGAACCTCGACTCTCCGCCGGAGACAGTGAAAAAGGCCAGAACCAAACGGAGGAGCAGCTATGCCGGACGAACTACTGCAACGGCCGGAGTACATGGACGTGGCAGCATTGGTACCATAAGTTCTGGAATAATCAAATCATTTCGGGAACGTTTCCTCAGCAACTCATCTGGGGACTCCGGCAAGTATAGAAAACTTAGGCAAAGGGATGCCGAGTCTGGCAGAATGGAAGCCAGTGGATCAAGTTCATCGGGAGAAAATGAGGACCCCAGCAGCAGTAGTAGTGTCGAGGATCTCTTTGCCAATGAGGCAGAACGTCGCAATTGGCACAGGAAAACCTCGGAGAAGCGACGAAGGAATGCCAGAAAAAAG
Seq A exon
TTTCATCTGCCAACCACTGCCAATGCAGCTGCACATCATCAATATTATCGCTTCCACAAGCAACAGCAGCAGCAACATCAGCATCACCACCAACAACAACAGAGCTGCCTGCGACAGCAGCAAAGACAATTGCAATGGGAGCAGCAGCAGCATCAGCAGCTGCAACATCAACTGACCAACAGCTCCAGCGAATTCGATGAGTTCCATTGGCCCAGCAAGCAGACGGGTGGCGAAAATCTGGGTGGCAAAATCTATATAACACCCGCAGACATACCGCCGCCACCACAACCGCCCCATCAAAGTGGCAGCAACAGTCACAGCCACCACAATGGCAGCAACAGACAGCAGCAGCAACACCAGCAACATCCGCACTCCCTTCACTCCCACATCCATCCACATCCGCATCCGCACCACCAGCATGGACATCGCACACCGCCGCACCGCTGCAAATGCGAACATCCGTCCATCGAACTGATGGGCTACGAGGACTCAGTCATCGCCACCGCCACCGCCAGCAATACCGCCGCCAATGTGGGCGTGGCTGGGGGCGGAGGCGTGGGACGCCACCAGCATCCGCCCTACTACTACAAGGCTGCGGTGGGGCGACGTTCGAGCGCCAAGCTGCACGAATCCATGCTGGGCGGCGGGAGCAGTCTGGAGGACGACGACGGGACCAGTGCCGGCAGCTTCGGGGAGGGCATGTCGCGGTTCAAG
Seq C2 exon
AATCTAATGCATACCAAGGAGAAGAAGCGCCGGGTGCGAATCATCCTGACTGTTGTAACCACGGTCATAGCGGTTGCTCTATTGGCCACGGCCCTGGTTTTCATTCTCCGGACGGATGAAAAGGATGCCGACGACTCTGACTCAAACTCAAACAATGCCATCGATTTGGAGGATGTGCTAAGTGGTCAACTATATGCCAAGCGATTCAACGGCAGCTGGAGCAATGGAAACAGTCTCATTTACAAGGAGAATACG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0259175_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.825 A=0.912 C2=0.086
Domain overlap (PFAM):
C1:
PF105004=SR-25=PU(77.0=83.2),PF060247=DUF912=PU(37.9=24.1)
A:
PF0260110=Exonuc_VII_L=PD(90.9=63.0)
C2:
PF105004=SR-25=PD(21.6=37.6),PF060247=DUF912=PD(59.8=61.2)
Main Inclusion Isoform:
FBpp0288926
Main Skipping Isoform:
FBpp0288924
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAGCAACTCATCTGGGGACT
R:
GTCGGCATCCTTTTCATCCGT
Band lengths:
347-1061
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)