DmeEX0008973 @ dm6
Exon Skipping
Gene
FBgn0265297 | pAbp
Description
The gene poly(A) binding protein is referred to in FlyBase by the symbol DmelpAbp (CG5119, FBgn0265297). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:18140078..18147191. Its molecular function is described by 6 unique terms, many of which group under: organic cyclic compound binding; binding; heterocyclic compound binding; nucleic acid binding; RNA binding. It is involved in the biological process described with 12 unique terms, many of which group under: regulation of cellular macromolecule biosynthetic process; chemical synaptic transmission; compound eye photoreceptor development; cellular aromatic compound metabolic process; cytokinesis. 26 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; sarcomere; neuromuscular junction; adult thorax; cellular process. The phenotypic classes of alleles include: sterile; cell cycle defective; increased mortality; phenotype.
Coordinates
chr2R:18140777-18144897:+
Coord C1 exon
chr2R:18140777-18140954
Coord A exon
chr2R:18141488-18141672
Coord C2 exon
chr2R:18143413-18144897
Length
185 bp
Sequences
Splice sites
3' ss Seq
TTAATTGTTAAAAATTGCAGGTA
3' ss Score
6.02
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
CTATGAGTCGTGTAGAGTCCGTTTACGTGAGCGGTCGTGGATTCGCTTTCAGCACACGGCTTATCACATATTTTTTGTGAAGAAAAAACATATAAAAAATAAAAAAAAATATTAAAACACAAAAACGTAACAAAAAAAATTGTAAAAAGTAGCAAAAAAAATCGAGCGTGTTTGAGAA
Seq A exon
GTAGACCTGATCACCAAATATGGCTTCTCTATACGTCGGTGATCTCCCACAGGACGTCAACGAATCGGGACTTTTTGACAAGTTCTCGTCTGCTGGTCCAGTGCTGTCCATTCGTGTCTGCCGCGATGTGATTACCCGTCGCTCGTTGGGCTATGCCTACGTCAACTTCCAGCAGCCAGCCGATG
Seq C2 exon
CTGAGCGTGCTTTGGACACCATGAACTTTGACCTGGTTCGCAACAAGCCCATTCGCATTATGTGGTCTCAGCGTGATCCTTCTCTTCGTCGCTCAGGTGTGGGCAACGTGTTCATCAAGAACTTAGATAGGGCCATCGACAACAAGGCAATCTACGACACTTTCTCCGCCTTCGGCAACATTTTAAGCTGCAAGGTAGCCACCGATGAAAAGGGCAACTCAAAGGGCTATGGATTCGTCCACTTCGAGACCGAGGAGGCCGCAAACACGTCCATCGACAAAGTCAATGGCATGTTGCTCAACGGCAAGAAGGTCTACGTGGGTAAGTTCATCCCGCGCAAGGAGCGCGAGAAGGAGCTGGGCGAGAAGGCTAAGCTCTTCACCAATGTATATGTGAAGAACTTCACTGAGGATTTCGACGATGAAAAACTGAAGGAATTCTTTGAGCCCTACGGCAAGATAACCAGCTACAAGGTCATGTCCAAGGAGGATGGCAAGAGC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0265297-'1-5,'1-2,3-5
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.284
Domain overlap (PFAM):
C1:
NA
A:
PF0007617=RRM_1=PU(73.2=92.9)
C2:
PF0007617=RRM_1=PD(25.4=3.6),PF0007617=RRM_1=WD(100=14.1),PF0007617=RRM_1=WD(100=13.9),PF0007617=RRM_1=WD(100=14.1)
Main Inclusion Isoform:
FBpp0085915

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0085917, FBpp0085919
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGTGGATTCGCTTTCAGCAC
R:
CACCTGAGCGACGAAGAGAAG
Band lengths:
243-428
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)