DmeEX0009059 @ dm6
Exon Skipping
Gene
FBgn0010309 | pigeon
Description
The gene pigeon is referred to in FlyBase by the symbol Dmelpigeon (CG10739, FBgn0010309). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:19186043..19189938. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of amyloid-beta formation. 10 alleles are reported. The phenotype of these alleles manifest in: synapse. The phenotypic classes of alleles include: memory defective; learning defective; viable; neuroanatomy defective; partially lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
Coordinates
chr2L:19188591-19189938:+
Coord C1 exon
chr2L:19188591-19188805
Coord A exon
chr2L:19188876-19189100
Coord C2 exon
chr2L:19189446-19189938
Length
225 bp
Sequences
Splice sites
3' ss Seq
TGCTTAATGTATTCCTTCAGATA
3' ss Score
8.87
5' ss Seq
GCGGTAAGA
5' ss Score
9.63
Exon sequences
Seq C1 exon
TGACCAAATGGCTGCCAATCAACAGCACTCTCTGTTTCTAATCCTCGAGCGCTATTGCCTGGCTGTGGAATCGATTGCGTTTCCCCTGCCCGAGGGTTTCTCCTCGTTCTTCACCTACTTGGGCTATCGTGCGCTGGGCTATGATATGTTTCTGCAGTATGTGGAAAATCATGTGTTCGAACTGCAAGTGGATGTGATGAAGGCCATTGTTTTCG
Seq A exon
ATATTGAAGATTCTCCACTGGGCATTGAGCGGAAGCTATCACTTTTGTCTGCTCTGCCCAAGCAGCGTGCTCAAAGGTTACTCAAATGCTGGCAGCATCCGGACAGCCTTATGATCCGCGGACGCGAGCATGCGGCCAACATTCTGTCGGGTCAGCAGCAGGAGGTGTTGCACCAGCAGCGACCCACGGCCTGCGTGAATCAATCGCGAAATAATGCGCGGAGCG
Seq C2 exon
ATCTAACTGCCGAAGCCCTTTCGCCACTGGACTCCTTTCTGGACCTGCTGACTGCGAAGGCCAGTCTAAACGAATTGGACTACAATCTGCTTATTGAAACTACTCTAAGCTCCATCGATCAGCTGAAACTGGAGGCTTGAATTTAATGTTAAGAGTAACTAATGAAGTATTGTGTCAAATTATCAAGTACTTAGCCAAGGCCAGTTTGCAAATATTCCAAAGATTTGATTTGTCAAATGTATTAGTTAAGATTCTTCTCGTGCAGCTTTGATTTTTGTTAGGGTTCTTCTGTGTGCTTTTAGTATTAATTTTCTGTTCCTATTATTTGTGTAACGACTGATACACATTCCAAGTCTGTAATTATAAATTATTTATGTTGTTAATTGATGTACCTAAAATCATGTACGTATTTATATATTCTGTACTTATTTATTTTATGCTTCTGCAAGCTTCTGTCTCTCTTTCTGTAATAAACTAACGATTTATAAAGTAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0010309-'7-7,'7-5,8-7
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.070 C2=0.022
Domain overlap (PFAM):
C1:
PF149591=GSAP-16=FE(63.2=100)
A:
PF149591=GSAP-16=PD(10.5=15.8)
C2:
NO
Main Inclusion Isoform:
FBpp0080735
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0291717
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTATTGCCTGGCTGTGGAAT
R:
GCCTCCAGTTTCAGCTGATCG
Band lengths:
301-526
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)