DmeEX0009205 @ dm6
Exon Skipping
Gene
FBgn0003187 | qua
Description
The gene quail is referred to in FlyBase by the symbol Dmelqua (CG6433, FBgn0003187). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:17486806..17497208. Its molecular function is described by: actin filament binding; actin binding; phosphatidylinositol-4,5-bisphosphate binding; calcium ion binding. It is involved in the biological process described with: actin polymerization or depolymerization; imaginal disc-derived wing hair organization; ovarian nurse cell to oocyte transport; barbed-end actin filament capping; actin filament severing. 42 alleles are reported. The phenotypes of these alleles manifest in: nucleolus; oocyte; actin cytoskeleton; cellular anatomical entity; egg. The phenotypic classes of alleles include: viable; female sterile; mitotic cell cycle defective; fertile; wild-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed during late pupal stages.
Coordinates
chr2L:17489693-17497208:-
Coord C1 exon
chr2L:17496735-17497208
Coord A exon
chr2L:17491802-17491851
Coord C2 exon
chr2L:17489693-17489902
Length
50 bp
Sequences
Splice sites
3' ss Seq
AGCTGTGCTGTATCTTTCAGATA
3' ss Score
10.39
5' ss Seq
ACGGTAACT
5' ss Score
7.53
Exon sequences
Seq C1 exon
CGTTCAGTCGCCAGTCGACTTTTCACGGGTTAAGTTAGACGTTAATGCCACCGATCAGCGAGCGGATCGCACGACTATATCCTTTTGTTTGACTTCCGCTTGACGTTAATTCGGGTTAATTTGTTTGGAAAGTGCGCAAATAAAGTTGCAGTGCCAAAAGACGCGTTATCACTTGTGTGGCGCTCTCTTTTTCCCACTAACGGTAAACTGTGCGAAGAAGCGCGCGAAAGCGAATTGCAAAAAAAGGCGGCCAAACAAAGCGAATGCCAAAAAGGTGACAGCCATAAACACAACAAATAGTCCGCGAAGTGCGAAAAAGTTAATTAGATTGTTTGCTTTTGGAGTTGCAACAACAATTGCACCTGCCCCATTCCATTTCTACACAAAAAAGAAACAAGCGAATACTCTAATTTGCATTGTAGCGCAGCCGCAAATTGGACCACAAAAATGCCGCCGTTTAATTTCATCAAGCAG
Seq A exon
ATACAGATACATCCGCGCACATGGAGCTATCGCTGTCACCAAAAGAAACG
Seq C2 exon
GAGATCCGTCCCAACACCATTCCGGACTTAAAGGTGGATGCCACATTTCGGAAGGTGGCTAAACATGCGATTACCTTTGCGATTTGGAAGATAGACGAGGATCGCCTGGAGGCGGTACAAAGATCACATTATGGCACCTTCTACGATAGCTGCGCCTACATTATCTATGCAGCAAGTTTGTCGGGGCATTATGCCAATCACGAAACCATC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0003187_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. ATG)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.127 C2=0.036
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0062617=Gelsolin=PU(37.1=51.4)
Main Inclusion Isoform:
FBtr0080996fB1041
Main Skipping Isoform:
FBpp0080549
Other Inclusion Isoforms:
FBpp0080550, FBpp0297295
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTGCCCCATTCCATTTCT
R:
GGAATGGTGTTGGGACGGATC
Band lengths:
138-188
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)