DmeEX0009344 @ dm6
Exon Skipping
Gene
FBgn0016754 | sba
Description
The gene six-banded is referred to in FlyBase by the symbol Dmelsba (CG13598, FBgn0016754). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 3R:23894174..23922973. Its molecular function is described by: chromatin binding; DNA binding. The biological processes in which it is involved are not known. 14 alleles are reported. The phenotype of these alleles manifest in: wing vein. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.
Coordinates
chr3R:23895324-23897191:-
Coord C1 exon
chr3R:23897063-23897191
Coord A exon
chr3R:23896209-23896608
Coord C2 exon
chr3R:23895324-23895426
Length
400 bp
Sequences
Splice sites
3' ss Seq
TGTGTGTGTGCCTTTCGTAGAGT
3' ss Score
9.38
5' ss Seq
AAAGTGAGC
5' ss Score
5.89
Exon sequences
Seq C1 exon
GCATTTGTAAGAACAATGTGTTTACCCAGCCCAGTGGGATCTACAAGCATTCGGAGCCAAAGATCAGACGCATCCACATCACCTCACAGACGTCGGCGGAGAACGGAATTAGCCTGATGCAGGGACAAG
Seq A exon
AGTCGCCCACCACAACGCAGCTGCTTTCATCAGTTCCAACCGCTCAACCAACAGTCGAGAAGACGACGGTCAGGACGCCCACGAAACGTTCGCGCCGACCGCAACGAGGGGCAGCGCGTGCGGCGCCCTCGGCGTCTGATAAAAGTTTCCCGCTGCCACCACGATCCTTTGCCATTGGGGAACTGATATGGGGTCCAGCTCGGGGCCATCCCGCCTGGCCCGGAAAGATTGTCAAGATGCCAGACGGAGTGTGCACGCCGTCGCAGCAATTCGACCACGTCTGGGTTCAGTGGTTCGGCGGCGGCGGTCGTTCGACCTCCGAGCTAATTCCGGTCAACTCATTGCAGAGTCTCTCCGAGGGTCTGGAAGCACATCACAAGGCCCAGAAGGATACGAGAAA
Seq C2 exon
CCTCCTCGACACCCGCAGCCACATCCTCGTCATCCGCAACCATCTCTGCTGTTCCCGCATCAGCAGGACCAGCTGTAATTGGCGGACAACAGCAGTATCAGCA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0016754_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.888 A=0.733 C2=0.885
Domain overlap (PFAM):
C1:
NO
A:
PF0085512=PWWP=PU(80.2=57.5)
C2:
NO
Main Inclusion Isoform:
FBpp0303406
Main Skipping Isoform:
FBpp0300787
Other Inclusion Isoforms:
FBpp0111801, FBpp0111802, FBpp0300786
Other Skipping Isoforms:
FBpp0300788, FBpp0307193
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATTTGTAAGAACAATGTGTTTACC
R:
TGCTGATACTGCTGTTGTCCG
Band lengths:
232-632
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)