DmeEX0009625 @ dm6
Exon Skipping
Gene
FBgn0265630 | sno
Description
The gene strawberry notch is referred to in FlyBase by the symbol Dmelsno (CG44436, FBgn0265630). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:13195499..13211674. Its molecular function is described by: histone binding; chromatin DNA binding. It is involved in the biological process described with 7 unique terms, many of which group under: Notch signaling pathway; instar larval or pupal morphogenesis; positive regulation of transcription, DNA-templated; regulation of signal transduction; neuron differentiation. 30 alleles are reported. The phenotypes of these alleles manifest in: gonad; embryonic/larval central nervous system; presumptive embryonic/larval peripheral nervous system; ommatidial precursor cluster; embryonic/larval nervous system. The phenotypic classes of alleles include: lethal; phenotype; some die during P-stage; increased mortality during development.
Coordinates
chrX:13200467-13204150:-
Coord C1 exon
chrX:13203710-13204150
Coord A exon
chrX:13202740-13203057
Coord C2 exon
chrX:13200467-13200904
Length
318 bp
Sequences
Splice sites
3' ss Seq
ACACTTGGTGCTCCAATCAGCCA
3' ss Score
3.39
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
Exon sequences
Seq C1 exon
GTGGAGGTCGCGATTTGAACACAGCCGTTACGTACGCCCAAAATATCCGTAGCGGAGTGGGCGTGGCGCCCAAAGGCGGTATACCCATACCCATAAGTGGGGCGAAAATTGTTGTTGGCAATAATAAAATCAAGCCAATATCGTTGTTGCGCATTAACAACAATAACAACAATATAGTCACCAGTGTTAACAATAGAAACAACAACAATATCATCAGCACCAACGGCAGCAGCAATAACAACAACAATAGCATCAACAACAACAGCCAGATAATAAAAACAACAACAGTAACAACAACACCAACCACTGTGGGTGCTACGCCAACAGTTGGAGGCGTGGCACTGGGCGGAAAGCTAACAGTGATACCGATAGCAGGGAGAAACGTAGCCCTAGATAATAATTTAAGCAATATGCCAAAGAAACTGAATAACATGGTAACGG
Seq A exon
CCATGGGCAGTCCAGCGGCCAGGAGCAGCGGCAATGCTGGGACGACTGGTTCGTCCCAGGGTGGTGCCATCGGCTCCACCAGCAGCTACTTGAACAGCCTGACCACCAACGAACTGATGAACCTGGCCGCCTATGTGGCCGCCAAGGGCAGCAACGCCCCACCGCCACCGCCGCCGTCCACAGCCGCCAATTCGGTGAGGCATTCACCAACAGGCGGCATTCCCAATCCCGGTGGCAATTTCTTTGGCGGATCGGCGGCGGCGTCCACTTCAGCCTCTGCTGCTAATTTTAATATGGCCGCGTCTTTATTGGCGCAGA
Seq C2 exon
TGAGTTATGCAGGCGGAGCTTCCCAAATTCGCGCCTTAAAGGTAGCCGGAAATATTGGCGGAGTCGGGAATAATCAGAAGCCGCCACCAATAGCCACAACTCCCGGAAGCGGAGGACCGGCTGGCGGAGCACCTGGTAGCGGAGTGAAGGGGAACAACTCAATGATGGAGGCCGTACAGAAACTGATAGCAATGAATCCGGAATACCTAACCAGTGGCATACCGAATACCGTATTCCAGATGTTTATGCAATCAATGCAACGTCCACAGGCAACTCCGTCGCCGAATCAGCCAATGAATCCCGGCGCAATGGTGACCAGTGCAGCTGCAGCGGCTGCCCACGCCTCAGCGGTTGCCTATGTCCAGCAGGAGGAGGATGAGGTCGACTACGAGGAGATGGGCGTAGCCGAGACATATGCCGACTACTGGCCTGCGAAAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0265630_MULTIEX1-1/2=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.543 A=0.626 C2=0.440
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0309425
Main Skipping Isoform:
FBpp0309424
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCAATATCGTTGTTGCGCAT
R:
GGCTACCTTTAAGGCGCGAAT
Band lengths:
355-673
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)