DmeEX0010172 @ dm6
Exon Skipping
Gene
FBgn0265434 | zip
Description
The gene zipper is referred to in FlyBase by the symbol Dmelzip (CG15792, FBgn0265434). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (7 unique). Gene sequence location is 2R:24990570..25011965. Its molecular function is described by: actin filament binding; protein binding; ATP binding; motor activity; myosin light chain binding. It is involved in the biological process described with 28 unique terms, many of which group under: open tracheal system development; midgut development; gland development; wound healing; cellular response to external stimulus. 63 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor; somatic precursor cell; filamentous actin; actin-based cell projection; denticle. The phenotypic classes of alleles include: some die during larval stage; wound healing defective; increased mortality; phenotype.
Coordinates
chr2R:24997209-25000160:-
Coord C1 exon
chr2R:25000039-25000160
Coord A exon
chr2R:24997578-24997697
Coord C2 exon
chr2R:24997209-24997301
Length
120 bp
Sequences
Splice sites
3' ss Seq
CCATTCCCACCTAATTGCAGAAC
3' ss Score
7.51
5' ss Seq
GAGGTAAAC
5' ss Score
7.2
Exon sequences
Seq C1 exon
ATCGCGAAGACCAATCGATTTTGTGTACTGGCGAATCGGGTGCTGGCAAAACGGAGAACACCAAGAAGGTCATCCAATTTCTAGCCTATGTGGCAGCTTCGAAACCCAAGGGCTCGGGTGCG
Seq A exon
AACTTCTCGGTCAACACAAACAAGTACATAAAGGTCAAGATTATGGCCCAAAATCAGAATCAGACGATCGAGGTAGTCAATGGATTGAAGATGGTGGAAGTTAATTCCAACTGTCAAGAG
Seq C2 exon
GGCGAGCTGGAGCAACAGCTGCTGCAGGCAAATCCCATTCTGGAGGCCTTTGGCAACGCCAAGACGGTCAAAAACGATAACTCTTCACGTTTT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0265434_MULTIEX1-3/3=C1-C2
Average complexity
ME(2-3[100=100])
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.098 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(5.5=100)
A:
PF0006316=Myosin_head=FE(5.4=100)
C2:
PF0006316=Myosin_head=FE(4.2=100)
Main Inclusion Isoform:
FBpp0072306
Main Skipping Isoform:
FBpp0297531
Other Inclusion Isoforms:
FBpp0072305
Other Skipping Isoforms:
FBpp0099894, FBpp0099896, FBpp0291728, FBpp0291729, FBpp0291730, FBpp0291731
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGCGAAGACCAATCGATTTTG
R:
CGTGAAGAGTTATCGTTTTTGACCG
Band lengths:
210-330
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)