Special

DmeEX6018263 @ dm6

Exon Skipping

Gene
FBgn0267431 | CG45784
Description
The gene Myosin 81F is referred to in FlyBase by the symbol DmelMyo81F (CG45784, FBgn0267431). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:567076..2532932. Its molecular function is described by: actin-dependent ATPase activity; ATP binding; microfilament motor activity; actin filament binding. It is involved in the biological process described with: actin filament organization; signal transduction; sensory organ development; vesicle transport along actin filament; sensory perception of sound. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
Coordinates
chr3R:1467146-1846163:+
Coord C1 exon
chr3R:1467146-1467258
Coord A exon
chr3R:1588295-1588538
Coord C2 exon
chr3R:1845561-1846163
Length
244 bp
Sequences
Splice sites
3' ss Seq
TTTTCTGTTTAATATTTCAGGTC
3' ss Score
11.04
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
GTAGCAGCGGCATTAAGAGAAATGAAGCGCGTTGATGAAGAACTAAAAAAGCGTGATGGAATCTATGAGCAATTAACCAGCATAACCACAAAAACTCTTGCTGATTGTGAGAG
Seq A exon
GTCAATACAAGAAGAACTAAGTGTGCTGGCTCATATTTCAGATAACATTCGCGCCTCAGCTAAGCCACTTTCCGATAAGAATGATTCTGACAGCAATACTGCGAGATCTTCAATTAAACAGAACACCGTTAACCTGGACAATATGTTTGATTTTTTATGCGAATCAAAGGGAGCATTTGAGAATGCACTTATTAAAGAAATAAATGACAACTGGAACAACTTGGTTAAAAATCTTGACGAAGAA
Seq C2 exon
ATAGGATTGTGTATACACACCGAAGACAGTTTTGATAGCCAAAAAACGGGAAAGCTTTTTACAACAAAGACCGTCCGAACTCTACCAGAACCAACTGTACCGCCCCCACCACCACCGGTATCTATAAGCGCAAATTTAAATTCTGAGCCAATATATGAGGCAATAAACTTATACAAGCTAACAACAACAAAAGAAATAAAAAAGGAAAAGTATATGTTACTTGATTACAAAAGCATTAAGGATAACAGTAAGAAGCCTTCTACTTCTTCTGTTTTTGTAAAATATCAAATTGATGAACGTGAGAATAGACGAAAACAAAGAGTGGAAAAAAAAATTCACGAACTAACATTAATTGATATTCACAAAGATATTCACATAGATAATTCATTTTACAATATCTTGGAATTCGCGGAAAACTATTTTAATACGCATGACCTTTCAAGTGATTGTAACTTTATTTCTACACCGACACAAAAGGGAAAAAGTTCTGATAAAACGGC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0267431-'17-22,'17-19,20-22=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.244 C2=0.244
Domain overlap (PFAM):

C1:
NO
A:
NO
C2:
NO


Main Inclusion Isoform:
FBpp0312365


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCACAAAAACTCTTGCTGATTGTG
R:
ACAAAAACAGAAGAAGTAGAAGGCT
Band lengths:
307-551
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)