DmeINT0001708 @ dm6
Intron Retention
Gene
FBgn0033983 | CG10253
Description
The gene Alkyldihydroxyacetonephosphate synthase is referred to in FlyBase by the symbol DmelADPS (CG10253, FBgn0033983). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2R:14929703..14934861. Its molecular function is described by: oxidoreductase activity; alkylglycerone-phosphate synthase activity; FAD binding. It is involved in the biological process described with: oxidation-reduction process; ether lipid biosynthetic process; lipid biosynthetic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages.
Coordinates
chr2R:14931152-14932488:-
Coord C1 exon
chr2R:14932402-14932488
Coord A exon
chr2R:14932341-14932401
Coord C2 exon
chr2R:14931152-14932340
Length
61 bp
Sequences
Splice sites
5' ss Seq
AAAGTGAGT
5' ss Score
8.4
3' ss Seq
CATATCCCATTTCCCCACAGATA
3' ss Score
11.37
Exon sequences
Seq C1 exon
ACATGAGGCGCTTAAGTGGTTCGGATGGGGATATAACGACTCGCAGTTTTATGGTAAGGATGGTATCATCTGTTTTCGCGGTGAAAA
Seq A exon
GTGAGTAGAGTACATTCAATTTCCGAATTGAATAGTGAAAGCATATCCCATTTCCCCACAG
Seq C2 exon
ATATCCCCTCGGTGGATGCGAGCTGCCCAGTTTCACCAAGTGGGTGGAGAAGAAGTTCGATCTGCGAGTGGATACCACCAAGCAGTATCCCCAGTTGCCACGAACGTATCCGCGGCCAGTGGAGAACGCACCCTTCCTGCACGAACTGAAGGGCACCACCCAGGTGGATTACTCTGCGGAGGGAATCGATCGGTTGGTGCGGTGCCATGGCCAGACCCTCAACGATATATACAGCCTGTGGCACCACAAGTTTCGACGGATACCCGATTTGGTGGTGTGGCCACGTTGCCACGATGAGGTAGTCCAGTTGGTGCGGCTGGCCAACAAGCACAATGTGATGCTGGTGCCTTTTGGTGGTGGAACGAGTGTATCGGGAGCCATCACCTGTCCGCAGAACGAGAGCCGAATGATCTGCGCCCTGGACACCTCTCAGATGAATCGACTATTGTGGCTAAACCGGGAGAATCTCACCGTATGCTTTGAGTCCGGCATTGTGGGTCAGGATCTGGAGAGGGTGTTGCGAAGTGAAGGTCTGACAGTTGGCCACGAACCGGATTCGTATGAGTTCAGCACCCTGGGCGGCTGGGTGGCAACTCGTGCATCTGGCATGAAGAAGAACGTCTATGGTAACATAGAGGATCTGGTGGTGCGAGTTAGGATGGTCACTCCGTCGGGAACGCTGGAACGTGAATGCAGTGCGCCGCGCGTGAGTTGTGGACCTGATTTCAACCATGTCATCTTGGGATCCGAGGGCACTCTGGGAGTAATCACCGAAGTGGTGCTCAAGGTGCGTCCCCTGCCATCGTTGAGGCGTTACGGATCCCTGGCCTTTCCCAACTTCGAGCAGGGAGTGCTCTTCATGCGCGAAGTGGCGCGGAGGAGATGTCAACCCGCCTCCGTCCGGCTGATGGACAACGAGCAGTTCATGTTCGGCCAGGCCCTGAAACCGGAGAAGTCCTGGTGGGCCAGTGTGGTGGATGCCATGAAGCAGCGCTACGTTACCTCCTGGAAGGGCATCGATCTCAATCAGATCTGCGCGGCCACCTTGCTTTTCGAGGGCGATTTAAAGGATGTCCAGCGGCAGGAGGCACTCATTTACGAGATTGCCGAAAAGTTTCAGGGATTTCCGGCAGGTGGACAAAATGGGGAACGGGGCTATATACTCACCTTTGTGATTGCCTACATTAGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033983:FBtr0087428:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.008
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0156518=FAD_binding_4=WD(100=36.0),PF0291314=FAD-oxidase_C=PU(47.8=32.7)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0086558
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0292772, FBpp0292773, FBpp0292774
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGAGGCGCTTAAGTGGTTCG
R:
TCGAACTTCTTCTCCACCCACT
Band lengths:
145-206
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)