Special

DmeINT0001859 @ dm6

Intron Retention

Gene
FBgn0036273 | CG10426
Description
The gene Inositol polyphosphate 5-phosphatase E is referred to in FlyBase by the symbol DmelINPP5E (CG10426, FBgn0036273). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:12277655..12281476. Its molecular function is described by: phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. It is involved in the biological process described with: phosphatidylinositol dephosphorylation; sensory perception of sound; protein localization to cilium. 15 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; synapse; Johnston organ neuron; scolopidial cilium. The phenotypic classes of alleles include: auditory perception defective; fertile; short lived; neuroanatomy defective; partially lethal; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr3L:12277655-12278283:+
Coord C1 exon
chr3L:12277655-12277736
Coord A exon
chr3L:12277737-12278225
Coord C2 exon
chr3L:12278226-12278283
Length
489 bp
Sequences
Splice sites
5' ss Seq
GCGGTAAAT
5' ss Score
6.76
3' ss Seq
GATTTTCTGAATCCTTTCAGCTC
3' ss Score
7.6
Exon sequences
Seq C1 exon
TTTTGCCACCCCTAAATCGCAGTTCCCACGACAAGTTCCGCACTTGCTCGGAGTTTTTGGGTGTAAACAACATTGGAACGCG
Seq A exon
GTAAATCATACAAAAATTACATAAATCGCATAGGTGACAGCAGCGTGGAAGGGTAGTGCGTACCAGTGCGGAACATGAAAAGCACACCAAGAGCGAAATCAATGCGCACCTGAACCTGAACTTGAATATCGCATGTGTGCTATGTGCTATTGTTGCTGCTTTTATGCTAGACGTAGGCCAACAACACAAGAACAACAAGGCTGCGCTGACGGGAACAATGGTCTGCTAATTATAAATCTCTCGATCCCAGAGAATCGAATCAGCCAGCAGACGACGGATATTGTGCTTGTGTTCAGACGTTCAGATGCTGAGTGCTCAGTGCTTGGATGCGTGGGCGCCGCAGCATGCCAATGTTGTTACGTCGTCGCCAAAGACCACCCTTCCGCGACCAACCACCCCCCAAATCGCCCACAATCCTCCCCATTTTATATATCGCGACGGTGTCGCCACAGTTATTACCCAGCATATTGATTTTCTGAATCCTTTCAG
Seq C2 exon
CTCTCTCGCCCCAAAGGATCTGCCCACATATGTGTTTTTTTTATTTAGTTGCTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0036273:FBtr0076007:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=NA
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
NA


Main Inclusion Isoform:
NA


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)