DmeINT0002085 @ dm6
Intron Retention
Gene
FBgn0032845 | CG10747
Description
This gene is referred to in FlyBase by the symbol DmelCG10747 (FBgn0032845). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:20089636..20091348. Its molecular function is described by: phosphoric diester hydrolase activity; glycosylphosphatidylinositol diacylglycerol-lyase activity. It is involved in the biological process described with: glycerophospholipid metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr2L:20089636-20091222:-
Coord C1 exon
chr2L:20090998-20091222
Coord A exon
chr2L:20090940-20090997
Coord C2 exon
chr2L:20089636-20090939
Length
58 bp
Sequences
Splice sites
5' ss Seq
CAGGTACGG
5' ss Score
10.88
3' ss Seq
GAGTCTGCAATCTAGTATAGGTT
3' ss Score
0.98
Exon sequences
Seq C1 exon
ACAATGCAGCCTCACTAAATATACTACGCAACAGTTAAACGAACCCCCTTGTGAAGCCCATGGATTATTTATGGATTATCCCCAACATCAACAACATCAACATTGGTGTATGTCTTCATAGAAAGGATTAGATAGGACAAGGAGGCACCATGTCCAAGGATCACTGGATGAGGGATCTGCCAAGCGAGTTGCGTGACCTGTCGATAATCAATCTGGCTATTCCAG
Seq A exon
GTACGGATGAGATCATCGTACTTGCTGAATTAATTGAGGAGTCTGCAATCTAGTATAG
Seq C2 exon
GTTCCCACAATTCGATGACTTATGGCATAAATAGCAAGTCCGAACTATCGCCAGATGCGGAAATTTCGATTAGGCGGTGGCATCGCTTCTTTCCCTGCTTCGTGCGCCGTTGGAGCAAGACGCAATCTTCTGGAACACTGGATCAACTGGAGCTGGGAGTGCGGTACTTTGACCTAAGGATAGCCCAGAAGGATGATAAGTTCTACTACTGTCATGGCCTTTTTGCCATGGAGATTTTTGAGCCACTTCTGGAGATTCGCCAGTTCGTGGACACCCATCCAGAGGAGGTGGTAATCCTGGATCTGCAGCACTTTTACGCCATGACAGTGGCTCATCACCAGAAGCTGCACAAGGATCTGATCCAGTTCTTCGCCCATCGTCTGTACTCCACAGTGGATGGTTCACTCAAGGATTGTACTCTGAATAGATGCTTGGAAATGCAGCGCAGCGTGGTGATCATCTACAGGCGATGTCCCATTCCACTGCCGCTGAGATTCTGGCCCAGTTATGCGTGGCCCACACCGTGGCCCAATAAAGCGAGTGTCAAGAAGCTGCAGTCCTTTCTGGAGGATTCCCTACTCTCGCGACAGCCCCAACAGGGTTATGTCTCCCAGTGCCTTATCACGCCCACTGGTCGCTATATCGCCTTCCGGCTCTTCTTCACCCTGAAGAGCACAGCCAAACGGGTGGACAAGAAGCTGCAGCCTTGGATTCAGGAACAGATTCCAGGTCCCTTCGAGCCAAAGGACGAGCCAAGGGTAAACGTGTTCCTGGCCGACTTCGTAAGCCTAAAGGGCGGACAGTTCTGCGATTGGGTAGTTGATCTGAACACAAAACTACTTGAGCAATTGGCTGGCGATAAGGAGCTGGAGTCCACTGAAGGCGTGGAAGAGGAGGAGGCCCAAGGTTGAAGATTTCCACAAGAAAGGCAGAGGGAACACATGGTTATTAGCCTGCGGTACTTTTAATATTTTTATAAACCAATATTTGGATGTTGACACAAAGTTGTTCGAAAACCGTGATAAACTTTCGAAGAGGTGATAATGAAGTAAATAATTATTTTAATGCCAGAGCAAACTATTATGTCACTTACGTACAAGCATGATTTGGATATTAAGTTATGTAAGACCAGAAAATCATTACAAAAACAAACTAAAGCTAGTGATTTATTTGATAAACTAATTGAAAAGTCTTTTTTTGTACCGCCACTTTAAAATATTTCCCAAAAGCCAGTTTCACTTGAAGGTGCTATCAATACATTTTATTGTTAAAAATCAATATACAAAAAATATATATTTAAAAAC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0032845:FBtr0081341:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.046
Domain overlap (PFAM):
C1:
PF034908=Varsurf_PPLC=PU(53.3=92.3),PF0038814=PI-PLC-X=PU(2.5=15.4)
A:
NA
C2:
PF034908=Varsurf_PPLC=PD(44.4=6.6),PF0038814=PI-PLC-X=PD(96.9=51.3)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0080873
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0304008
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGGATGAGGGATCTGCCAA
R:
GATGCCACCGCCTAATCGAAA
Band lengths:
147-205
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)