DmeINT0004569 @ dm6
Intron Retention
Gene
FBgn0030571 | CG14414
Description
This gene is referred to in FlyBase by the symbol DmelCG14414 (FBgn0030571). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is X:14580600..14582174. Its molecular function is described by: mRNA binding; RNA binding. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; short lived; viable; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chrX:14580740-14581039:+
Coord C1 exon
chrX:14580740-14580846
Coord A exon
chrX:14580847-14580964
Coord C2 exon
chrX:14580965-14581039
Length
118 bp
Sequences
Splice sites
5' ss Seq
CGAGTAAGT
5' ss Score
10.15
3' ss Seq
AATGCGGCGCCATCGAGAAGTTC
3' ss Score
-5.35
Exon sequences
Seq C1 exon
GCCGGAACGAGTGGGTCGGGTGGCTTAAGCGGCGGCGGCGGCGGCGGTGGAAACCCCGAGGAGGCGCGTCGCATCTGGGTTGGGAATCTGGACTCACGGATCACCGA
Seq A exon
GTAAGTTGTGCCTGGCATATATGCAGTGCGATTCCATGGTGCTAATAGTTCAATTTGCATTGCCCCCTATCGGTTTCAACTCCTCAAACTGATGCAAAAATGCGGCGCCATCGAGAAG
Seq C2 exon
TTCGACATGCTGTTCCACAAGGGCGGTCCCATGGTGGGACAATCCAGGGGCTACGCCTTCGTCACCTTTGCGCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0030571:FBtr0073930:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=0.569 A=NA C2=0.026
Domain overlap (PFAM):
C1:
PF0007617=RRM_1=PU(14.9=30.6)
A:
NA
C2:
PF0007617=RRM_1=PU(41.0=69.6)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0073747, FBpp0073749
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTGGGTCGGGTGGCTTAAG
R:
CTGCGCAAAGGTGACGAAGG
Band lengths:
174-292
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)