DmeINT0004764 @ dm6
Intron Retention
Gene
FBgn0037317 | CG14667
Description
This gene is referred to in FlyBase by the symbol DmelCG14667 (FBgn0037317). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:5375022..5376460. Its molecular function is described by: DNA-binding transcription factor activity; zinc ion binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr3R:5375022-5375924:+
Coord C1 exon
chr3R:5375022-5375216
Coord A exon
chr3R:5375217-5375277
Coord C2 exon
chr3R:5375278-5375924
Length
61 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGT
5' ss Score
9.65
3' ss Seq
ATTACCTGGAATTTGTTCAGCTG
3' ss Score
3.98
Exon sequences
Seq C1 exon
TTTATGATCTGGTAACACTTTCCGTCGCTGCGTTTTATGCTAAAAGTAAACACATTAACTTGATAAACAATGAACCTCGCCGACGTTTGCCGTATTTGCGCCAACAAAATTATGGGCCACCAGCGAGATCGCAACATATTCATTCACATGCGGGGAAAATATTTGGGTCAACTGAAGCTAATCACGGGAGTGGAG
Seq A exon
GTAGGTCGTTATGTCAGCTTCCGACCGCGCCAACAATTGTTATTACCTGGAATTTGTTCAG
Seq C2 exon
CTGACAAGAAACCAGGGGCTGCCGGAGATTGTTTGCGAGCGCTGCTTCTCCGAGCTGGACCTGGCCACCAAGTTCCGCGAGCGGTGCATCTTCTCGCAAAAGTACCTGCTGGATATCATAAAGAAGACCAGTGATCAAAGCACTGTTCACGTTGAGCTTAGTTCCGAGCCGCTGGACGAGCAACTGATCGATGCGGATCAATTGGAGACGCACTACGATGACGACCAGTACGTTTGTTATCAAGGCACGAAAGAGGAACACCAAGACCTAGAGGAAATCGAGCTGGATGACGACCCCTCTGCCGCTGTGATAGCGGCAGCAGAGGCGGCAGCAGAAGCGGCGCAGCAGGAGGATCTACAGGAGCAGGAAATGGAGCGGGCCGCCAAGAGGCGCAGTAACTTCTTTATCTGCGACGAGTGTGGAACCCTGTTCCACGATGCGTTCCTGTACACCGAGCATTTAAATGGGCACCAGAACCGGCGGGATATGAACCAGTTCTTCCCCTGCCCTGAGTGCCCACAGACTTTTAACAAGAAGGCGCTTCTCAAGCAGCATCGCACCCAGGTTCATTTAATTAACCGCAGGTTCCAGTGCACCATCTGCCACGAGGCTTTCGCGTCTCTGGGCGCTAAGTTGCGGCACGACAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0037317:FBtr0100433:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.134
Domain overlap (PFAM):
C1:
PF0777610=zf-AD=PU(47.4=85.7)
A:
NA
C2:
PF0777610=zf-AD=PD(50.0=17.6),PF0009621=zf-C2H2=WD(100=11.1)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0099852
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGAACCTCGCCGACGTTTG
R:
CAGCCCCTGGTTTCTTGTCAG
Band lengths:
148-209
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)