DmeINT0007314 @ dm6
Intron Retention
Gene
FBgn0023528 | CG2924
Description
This gene is referred to in FlyBase by the symbol DmelCG2924 (FBgn0023528). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:2264657..2270761. Its molecular function is described by: ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: protein K48-linked ubiquitination; protein polyubiquitination. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chrX:2266597-2267107:-
Coord C1 exon
chrX:2266820-2267107
Coord A exon
chrX:2266672-2266819
Coord C2 exon
chrX:2266597-2266671
Length
148 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
TTGATATCCGTGAAATGCAGAAG
3' ss Score
2.47
Exon sequences
Seq C1 exon
GTGGGCATACTGCTGCGTGAGCTGTGCCGCCTTCACAACGTTCCACTGCCACCCGACATCGATAATTTGGCTCTGCCGCTGCAAACGCCGCCGCCATCCGCTTCCCCCCTTCGCTGCGAGCAGAGACCAGGTGGTGGTGGAGCGGGGGGCGGTGGCGGACCCCACGGCAACGAGGAGACCGATTCGGATCAGGAGGAGATCGAGGATCCCATCGGCGAGAGCGAACAGGAGAGCGAGGGCGATGAGGACTTGCCGCTGGAAATGGATGATGTACGCAGTACAAGCAAG
Seq A exon
GTGAGCTTTAGGTGTAAAATTGTCTGCAATTAAATTATTTGTTGGTTTGGAGAGAGTTAGGTGTAACTTTGTAGTTATTTATATATAATTTCTGGGCGAAGATGTCAATCAATTATTCTTAAATCGTTTTGATATCCGTGAAATGCAG
Seq C2 exon
AAGGACGACATGGAAGTGGAACACCTAGCGACTCTAGAAAAACTGCGTCAAAGTCAGAGACAAGACTATCTAAAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0023528:FBtr0070412:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.802 A=NA C2=0.800
Domain overlap (PFAM):
C1:
PF0577317=RWD=PD(8.8=9.4)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0070396
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0290017, FBpp0311475, FBpp0312228
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACATCGATAATTTGGCTCTGC
R:
TGTTCCACTTCCATGTCGTCC
Band lengths:
258-406
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)