DmeINT0015510 @ dm6
Intron Retention
Gene
FBgn0037722 | CG8319
Description
This gene is referred to in FlyBase by the symbol DmelCG8319 (FBgn0037722). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9627321..9628676. Its molecular function is described by: zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 8 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
Coordinates
chr3R:9627321-9628676:+
Coord C1 exon
chr3R:9627321-9627909
Coord A exon
chr3R:9627910-9627970
Coord C2 exon
chr3R:9627971-9628676
Length
61 bp
Sequences
Splice sites
5' ss Seq
GAAGTAATT
5' ss Score
3.7
3' ss Seq
TTGTATATCTCATTCCACAGGGT
3' ss Score
9.97
Exon sequences
Seq C1 exon
AAAGAAGCACACAAAAGTTTATACCATAGTTTATTGTTTACCAAAAATATGACCTGTAGTTAAACAGCAGTTAAGCAATGGAGGACCTGTGTCGAATTTGTGGCGGGGCCTCGGAAAACATGCTGGGCATTTTCGACGATCAGGTGGAAGAATATGTTGATGGAGCCAAGCTCGCTGAGATGGTGAAGACATGTGCCGACGTGCAGTTGGATCCCGACGACGCTATGCCCCAAAAAATGTGCATTTCCTGTGTCCACGATGCACGAACTGCTTACGGATTCAAGCGAAGATGCGAAGAGAACTACAAGAAGTTCTATTTGGCGATATTAAATGGGCAGGTCATCAAGGACGAGCCCAACGAGGAGGATTTCCTATTCATTGAGAACCCAGACAAAGGCAATCTGGAAGCAAAGAAGAAACTCAACAAGGAAATTAAAAAGACACATCAAACAGCTTCCAGAACAACCAAGTCTTCCATAACAACCAGTAGAGCTGGCAGACAGCTAAGGAGTATAAAGAATCAGACTTTCAAATGCGAACTATGCATCAAACAGTTCAAGCGCCAAATAAACCTCCTGGACCACATGAA
Seq A exon
GTAATTACAATCAATACATATGATTTCACCTGTTCTTAAAATTGTATATCTCATTCCACAG
Seq C2 exon
GGTTCACAGCAATTCACACGTATGCCAAAACTGCGAAGAGCGTTTTCTGTTCAAGGCCGATCTGGATAACCACCAATGTTATCGCAATAGCAATTCCACCGTCGAGTGCCCGGAATGCTTAAAGGTCTTTTCAAGCACCCAGAGCCTGGACAGCCACAAATGCAAGGATATGCAGGAGCGTTCGCCCTTTCAGTGCCCCCACTGTCAGCAGGCCTTTACTCGCGAACAAAACCTCAAGGCGCACCTGTTGATCCACGCGGAATCGAAACAGGGAAACGGACCCCACAAATGTTCATACTGCCAAACGGGATTCTTCAACAAGTCGGCCCTCAAGGTGCACATCCATGCGCACATGGGCGAACGGCCGCATGCCTGTCCCTTCTGCGTGTCCAACTTCCGTTCCAAGCAGGCCCTTAAGGTCCACATCCGCATACACACGGGCGAGAAGCCCTACCAATGCCCCCACTGCCCCAAGACTTTTTCGGACAACAATAACCTGGCGAAGCACCGACGACGCCACTCGGATGAACGGCCCTACAAGTGTTCCATCTGCCTGCAGGACTTCCGGGAGAAACATCATCTGAAGCGGCACTTTCTGGGCAAGCATCGGGATGGAGATCAAAAGCTAAAGCTAAAGTGATACCTTAAATTCTTGACCAAATACCACGGCTTACTCGAATAAATAAATTAGGATTCGGTTATGTTT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0037722:FBtr0082077:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.175 A=NA C2=0.136
Domain overlap (PFAM):
C1:
PF0777610=zf-AD=WD(100=45.6),PF0009621=zf-C2H2=PU(87.0=11.7)
A:
NA
C2:
PF0009621=zf-C2H2=PD(8.7=0.9),PF139121=zf-C2H2_6=WD(100=11.7),PF0009621=zf-C2H2=WD(100=10.7),PF134651=zf-H2C2_2=WD(100=12.1),PF134651=zf-H2C2_2=WD(100=12.1),PF134651=zf-H2C2_2=WD(100=12.1)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0081555
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCGCCAAATAAACCTCCTGG
R:
ACGGTGGAATTGCTATTGCGA
Band lengths:
133-194
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)