DmeINT0015735 @ dm6
Intron Retention
Gene
FBgn0027602 | CG8611
Description
This gene is referred to in FlyBase by the symbol DmelCG8611 (FBgn0027602). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:17413267..17422145. Its molecular function is described by: ATP binding; RNA binding; RNA helicase activity. It is involved in the biological process described with: ribosome biogenesis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.
Coordinates
chrX:17414970-17419875:-
Coord C1 exon
chrX:17419448-17419875
Coord A exon
chrX:17415160-17419447
Coord C2 exon
chrX:17414970-17415159
Length
4288 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGT
5' ss Score
10.29
3' ss Seq
CTGCTCTTTCCCGCCCGCAGCCT
3' ss Score
10.6
Exon sequences
Seq C1 exon
ACTACATGGCTCCATGACGCAGACGGAACGGCAGGGCGTTTTTCGTGGCTTCCGCGATTGCGCCAGCTGCGTCCTGCTGGCCACCGATGTGGTGGGTCGTGGCATCGATGTTCCCGACATAAAACTGGTGGTGCAGTACACGCCGCCGCAAACCACCGCCGATTTTGTTCACCGCGTGGGTCGAACGGCTCGAGCGGGCCGAAAGGGCAGAGCCGTGCTCTTCCTGACGCCCAGCGAGGCCCAGTTCGTGCGGCATCTGGAGAAGAAGCGCATCCGCATCCAGCAGGGCGACATGTACGCCTACCTGCAGACCCTGCTGCCCAAGGACGATGAGGCCAGGACGGTGCAGGAGGCGGCCTCCAATCTGCAGCACAAGTTCCAGACGCTGCTCGAGGATGATCGCGAACTACACGACAAGTCCTGCAAAG
Seq A exon
GTAGGTTCCTCTATTACGGCTGCACTCCTGCTATAATACGTCTTTCACTTGAATTGCTTTTGAAAGCTGTGCATTTCTAATGTATCTGAGTATAGAATGTTTATCTTTTGAGTCGCTTTAACTGATTTTCCCTTCGTTAATGCTGACTGCAATCAATACCAATTAATCGTACCATTACCACAAGCAGGCTGTCGGATTTTTCGTATTCAGAATATACGGAGAACCCCTACGTATCCTGTGGCATTGGACGAGTTCCCATGGCACTTACTTTTCCAATTGCCCCAACTCCGATATCCCTGGACAAACTAGCAATTTAATCCTTTCACCAAAGAACATTAACTTTGTAATTACGATTTTTTACAACACTCGGGTGGCTGAATACAAAAAAGGCACCAAGACAAACACACAAACTCTCGGCTATTTTTCCAATTATAAGTTGGAAGCCCGGGCCACGCCCCCGCTCTTTTGACCGCCCCCAGACGGGCGCAGTTATCATCCACGGGGCAGCGCGCGTTAAAAACACAAAAATTATTTCATATTTGAAGTTAATTTCGATTGCGTGTCAAATGATTCCCCCACTTCCGCTCCGCTCCGTTCTGTTCTGTTCGCTCCTTCGACGACCTCCAACCACCCAACCACCCCGCCCAACACCACCCCCTCTCGACCACCAACCCCCTGGCTGGCCACCACCTTCGTCCGTCATCGCGGCAAGTGACCACCAGCGACTTCTTTCATCGCCCGATCCTTTTTTCTGCCTTCATTTATTTCCCATTTTATTTTATTTGCTTTTCAAAACGCGAGTAGGGGAGCTACCCATTAAAAAGTAGTGAAAAGGGTATATTATATCAAGGGATGTTTTACCCAATCTAATAAGAGTACAATCAAAAACTAAGCTACTGCTTTCACAAATATTTCTTAGATAACAAACTATTTCATTTATTAATCACTGAGAATAGGAGTCCAAGTAGTGACGAATCGCACCAGGAGGGATGTGTCTTTGCACACCTATTTATACGAAATGAAAATCTGCTGTAGTTGTTCGATCATAGCGTGAAAACTATAAGCAGTATGGGACTTAAGACTTATGAAGTTCAAGAGGATAAGCGGTGAATGTAAAAATTTTAAAAATTCAAACTGATGGGGCTGTTTTGTAGAAATGTTGTAACTTTACGTTTACACAGTGCACTGTTCCTAATAATATTTTCACTAGGTATATCCACGTCTGCCAGCTATGCATTTGTCTACCATTCTGCTGAAAATGTAATTGCAGCGTTGAAAAGGCTGGAAAAAAGTTAATTAGATGTTACCAAGGCGCGTTTGAAGGGTTGAGTTGAATCCAGACGATATTTTCCCCATTTTCCTGCGATTGAAACATAAAGGACTCATAAAAGCGAGCGGCAGGCGAGTGGAAACGATTCTAATCGAAAAGAGGCACCCAAAATGAATCATAAATGGGGAAAAGGAACCAAAAAAACCAGGCAATGCGAATGGGGAAGATCCTTTGATGGCTGAGATGGCGACTGCGACTCGAAACAGGAAACGGAAACTGAGCGAAATATCGCAAAACAATGGCAAAACAGCAAGATAAATAAAGGATGAAGGATATATAAATACATTCATACACAGATACATTCATATAGGCGAGAGCGAGAGTCGGTCAAAATGGCAACGCAAATTGCACTTAAGCGCCGAGTCAAGCGTCAAGACAGGAAGCCACTTGGCAAAACTTAAGAGCGGAGCAGCCAAAATGCCCGAAAGAGACGACACTAGGCGGGGCGAAAGAGACAGGGCGATACATCCGGATTCGAAGTGGGCAGGGGAAAGGGTCCTGCTGGAGGATGCAGTTTTCTACTGCTGCTGCTCTGCTGCGTCCAATCAAAAAGCCATTAAAAAGTATTACGCTTGAACAAAACTGTACAAAGCAGCAGATAAAAGGCAGCCAGAGAGGGACGGCAAATGTGGGTGGGTGGTGTACGAAAGAGACGGGCGATGGAGGGACAAACGAGCTGGGAAAGAGAGGGAAGAACATCTGCGACTTGCATTGCATCGGTAATTGAAACAATTTTCAACTTGGAATTCACTTTTTGTCTTCAGACTTCAGGCTTTTTAAAGTTACAGTAGTTCGTGCTACAGTGCGTTTCGCAGATGTAAGACAATGGTAAATGGTAGAGAACAGGGAATGTAAAATGTTCTCCAAAGAAAGAAGATTATATATTCTTCTGACTATACTTAAGTTCTTGCGGATTCTATAATTGAAGACTATTTATTGAGGTCTTCAATCAATGAAAGTAATAATGCGTTTTTAAACCACCTAAAATGTATTGTATATTTCAAAATAACCACATTTCCCGATATATCTCTCTCTCGAAAAACATCTGTTTTTCAAACGCAGGATAATCCGCTGACATGCACGCTGATCCTCATAGTTCCCCTTTGACTTACAATCATTTTTTTGGCGTATTCTATGGCATATTTTCACTGCCTTGGTCCATTGGCCCATTGTTTGCCATTATACCGCTAAATGGAAAGAGTTCTGTTAATGCCTTTCGAAACTAAGCCCCTGATGACCCATAAGTCCCACGCTTTAGGGCGACACCCCCGATTAGTGGGTATCGAGTGAGGAAATCCCATCTAGAACCCTTCGTCTGGGGGTTGCGAAATGGCAATGGTAATAGAATGGCAATGGGTGGACTGAAAAACAATCACAACAATTTGCCACGCCTACACAAACCGCATGGACACGCGCTGAAGAAACCACCACAAAATCCGGAGGAGGAACACCCACACCCACACCCACAGCCAGAGAAGACCAAAAACCACCGAGACAATGGCATAAAAAGCCATTTTGTGTGGCTTCTGCGGTGGATTCCGCACTCTCTCCTCCACCACGAAACTTCTTTCCACGAAATGACATTTATTTTATTCGCCACTTCCGGCTGGCAGACGTCTCTAAACATCCGCTGCCGTCATACTTTTTGTTTGCCTAATGTCTGCCACTTGGCCGTAATCGCATTTGCGGCAATTAAGCCAGAACCAGAAAGCCCAGGGCTTGACTTCGAGACTTTGGTCCTTTGGTGCTTTGGTCCCCAAAAAAGGACACTCGCCACTATGAACTGAACTGAACTGAAAACCGGGATGCAGAGAGCACTGCTGCGAGTTAATTGCCGGGGCAGGAACGTCTTTGCATCCATCTCTGCTGGGCTTGCCACTCCTCATCCCTGTCCTCCATCAGTGCTTCCTGTTTTTCTGGGATCTGGAGTTCGTTCCGGAATCATCCTGCCGTCGTCCTGTGGCTGGAGGATTCGGTGTGTGTGGCCGGGATGTGCGGCTCTTCGGTAGTCAATTACGAACTCCTGGGAACGGAAGGGCGACTAGTTTATTAAAGCTAATTTAGCGGCGTACAGTGTGATGAATAATGCAAACATAGTTGGTTATAAGAAAACATAACAGTAATTTAAAACATGATTTTCAAGTGAGAAGGGACAACACCTTTTGTTTAGGTTGTTATTTGCAATAGATAGAAGATGGATTAGCAATTCGTTTTTATGATTTTTTACCATACGTATTATTCATATTATAATTTTTCTTTATATATATATGAAGACAAAACTTGAGTCACTTTCTGCTGACACTCATTGCTCTACCCGAATCCTTTACGTATCCTTGGAAAGGACTCAACTCTCCCCGCAACTCGCACTCGCATCTGTCTGGTTTCGTTTCGTTATGTTTGGAAAGTGTTGTTCTTTGGGCATTTGCATTGCATTTCTCATTTCACTTCGCATCGCATCACATCGGATCGGATCGGATCGCATTTACATATCCCACTCCGCCGGATGGCGAGATGCTTATCGGGGTAACAATTGCGGTCCTGAGTGGCTGCTCCGCTCAACTGCTGCTCCGTTGGTAATTTGATATCATTGTTGTATAATTTGGAATTGCCTGGCATAAGTGCTGCGTAATTAGCAAGGACATGCCCACAACAGCGAACCACAAGCGTGTACACTTTGTTCCCGCGCCACATACATACATACTCGTATGTGTGGCTTGGTAACTCCGGTGAGCACAATGCCCGGGTCTATTGTGGTTGTGGATGCGATGTGAAATCCTTTGCTGACACTGCTCATTTGTCATTTTAACAAATTTATTTTGTAATGAATGCGGCTCACTCAGAACATGCACACACACACACACACGCATCGCTCAGCACTTAAGCCAAGACATCAATTAATTCTAAAGGCATTAACATTAACATCTCCGCCCTCTTCCTTCTGCTCTTTCCCGCCCGCAG
Seq C2 exon
CCTTTGTGTCCTGGATGAAGTTCTACTCGACGTTTCCCAAGGAGCTGAAGCCCATCTTCAACGTGCGCATCGCCCACATGGGCCACTTCGCCAAGAGCTTTGCGCTCAAGGAGGCGCCCTCAAAGTTCGCCGCCAAGCACGCCGCCCCCAAGGCGGCCCCGCCCACCAACCGACTGACCTACACGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0027602:FBtr0074439:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.090 A=NA C2=0.312
Domain overlap (PFAM):
C1:
PF0027126=Helicase_C=PD(86.8=45.8),PF139591=DUF4217=PU(33.8=15.3)
A:
NA
C2:
PF139591=DUF4217=PD(64.6=65.6)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0074214
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0074213
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)