DmeINT0020412 @ dm6
Intron Retention
Gene
FBgn0031463 | G6P
Description
The gene Glucose-6-Phosphatase is referred to in FlyBase by the symbol DmelG6P (CG15400, FBgn0031463). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2814336..2815760. Its molecular function is described by: glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. 10 alleles are reported. The phenotype of these alleles manifest in: adult NPF P1 neuron. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.
Coordinates
chr2L:2814336-2814756:-
Coord C1 exon
chr2L:2814638-2814756
Coord A exon
chr2L:2814590-2814637
Coord C2 exon
chr2L:2814336-2814589
Length
48 bp
Sequences
Splice sites
5' ss Seq
GCTGTAAGT
5' ss Score
8.56
3' ss Seq
CTGCATCAACCTCATTCCAGGGA
3' ss Score
6.57
Exon sequences
Seq C1 exon
GCATTTAAATGGTGTCCAGAACCCACATATTTGCGTCATGAAGTTGGTCCAATCTTTGCACTTGTCAGAGATCTGGGAAATCTAATGGGATTGGCTTTGGCCTCGCCACTATATAAGCT
Seq A exon
GTAAGTCTGATTATTTTGGATACACAAACTGCATCAACCTCATTCCAG
Seq C2 exon
GGAAATGAAACAATCATCATTTTGGCGGCGATGCCGATTCCTTGGAGTTCTGGAGTTTGTCAACTATGGATTGCGCTTTTCCACGTTTAAGCAGTCTGGTCGCTTCGTTTTCTTGACCTATGAGTTCTTAAGAAATGTCATTCATTCCCTAGTACTGATTAAGTACGTATCGAAATTTTACTAGAATAGAGGCTTTTCTAATTTTGTACAGATAAAAGAAAATATAAAAAACAATACTGGGACGAAAGTAAAAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0031463:FBtr0113017:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0111930
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCGTCATGAAGTTGGTCCAA
R:
CCAGAACTCCAAGGAATCGGC
Band lengths:
141-189
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)