DmeINT0021459 @ dm6
Intron Retention
Gene
FBgn0264005 | Hmx
Description
The gene H6-like-homeobox is referred to in FlyBase by the symbol DmelHmx (CG43748, FBgn0264005). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:17558930..17569097. Its molecular function is described by: sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: negative regulation of transcription, DNA-templated. 16 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: flight defective; viable; lethal; visible.
Coordinates
chr3R:17558930-17565563:+
Coord C1 exon
chr3R:17558930-17560193
Coord A exon
chr3R:17560194-17565453
Coord C2 exon
chr3R:17565454-17565563
Length
5260 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATT
5' ss Score
8.55
3' ss Seq
TCGCTTCTCTCTCCTTGCAGATT
3' ss Score
13.66
Exon sequences
Seq C1 exon
GACACGAGACCGGGGGTTAAAAATCCAGAGACTGAAACAATAAAAACACTAAACGATCGCTTTGCCACACACAAACACAAGCACACACACACACGCAGACACACACAAGCACTCGCATACATACAGAGACAGAAAGGACGAAGGACTCAGAACACAGAACTCAGGACTGCGTCTGTTAACAGCCGCATTTAAATTCAAATGCGAAACGTTGATCAAACGGTGCAGACGTGTTTCTCCCAACGGTAGCGCTCGGCGTTTTCCCTTAACGAGTTTTTCGTGGCACGACTGAAGTGTACAAGGTTTGGAAAATTCTTTATTTTCCTAACAAATATATATAAAACAAAAAAAAAAAAACACACACACAAGTGCAAGTTGAAGAACAAAAGTGCTGAATTAAACGTTTAAACTGCAAATCTAAGCAAAAATCTCAAGCTATGTCTTCCTCCGAGGCCGAAGTTGACATCAGTGTGGTGTCCAGTCCGGAGCCGAGTCCTTTGGGCGCCGCTGCCCGCGACAGTCCGCTGCTGGCCCGCTCGCCGGCCCGTTCCGCCGACGGCAGTTCGCCCCCGGCCACGCCTACCCATCGCTCCAATACGCCCAACACGGCCGCCGGCACGCCCACAACGTCCGCCTCGGGCGGCAATCACTTCCATCACAGTCCCAGCGGAGGCGCTGTGCCGCCGGCGGTGTTGCACCATCATCTGCAGCACCATCTGAGCAGCCTGGGCAGCCATCCGGTGGCGCTGCATCACGCGCTCCACACCTTTGGCCACTTGCATCCCGCCCACGGGGCCACACATCCCGCCCTGCTGCAGCACGCACTCACGCCCACCGGCCAGCAGCAGCAGCAACAGTTGCAGGTGCAGCAGCAACACCAGCAGTCGCATGTCGAGCGCCTTAGTCCGCCAATGAAGAGTCCGGAGCGGAATGGCGGCGATGAGGTGCAAGGACACAGTCTGAACAACAACAACAGTAAGGCCCTCAATCACAACAACACTTGCGCCTCGGCGGCCGCAGCGGCGGCAGCAGCAGCGGTGGCAGCGGCCAACCTGAGCAACAACAGCAACGACAGCAACGGGAGCAGCGGGGGCGGCGGCGGCAAGAGCACCACCGGCTCCAACGGATTCACCAGCTTCTCCATCTCCAGCATCCTGAGTCGCAGTGAGCCGGCCAAGAAGAACGGCGCCGCCGGACTTATCACTCCGATCCCGCAGTTGCCGCAACCAGGAGCCGGCGGTCCACAGGATGCGGCCATGTTGTCCAG
Seq A exon
GTAATTAAAAAACATTCCAGACTTGCTCTAGTCAAAAATAGCCCTCCCATTTCAAATGTGATTAATCTTGTAAATATGAAGTCGCCAAATTTAAAAATCTTAGTGTCAACATTTTACTTCAATTCATTTTAACAATTTAATCTGCAAAAATTTAGTCCATCCATCTGTCATATATAATTAGTTACTTCTGACGATATTCAGCTATTCCGCCTAATTTTGATCCGCAAGATATTTTAAAAAAATACAAACTCGAACTAAAATTTCATTCAAATTTTAACCCTATAATTACTGAAATTAAATGAGTATAATTTCATATGCCCAAGGATTTCCCATTGAATACCTTTTTTTGTAATAATAAAAATCACTCGTCTTAAGTACCATACCCATTTATTGCTCAGTGTAGGCGACCCAGATTAGGACGTTCGCCGGCGAACTGAAACCAAAAAGTCAAGCCTTGCCTCAATGAGCCCAAAACCCAAAGAGGCTGCCATTCCACTTGTTCGCCCTCGGGTTGGGCCAATTTTGTATAATCGTCCTAGGGGAAGACAAGGCAAGGTGACACAAATCTCTTCGCAGGAAGTGCACAAAGAGGAGAAATGGGATGGAGACGGACTGAGATGGTAGCCGGGAGATGGTCGATAAGACCGAAAATTGTTGGGCAAACGTTACACGAGACATTAAGTGGGTGAAGATGCAAATGGCTAAAGTACCATGCCATTGTGCTCCGAGAATCTAACGATTCCAAATTCCAGATGCCAGACAGATAAAGCAAATCCAATGGAACCGTTTTTAGTTGCACTGGACGCTAGCTGACCTCGAATATATGCAGAAAAGGTCTAAACCATTTTTGCCCTGCAATTTGGCCAGACTATCGAGTTACATAACATTTGTTAGATGAAATTTAATGCACCGCTTCGGGAATGAATGTAACCGACTGTCCGGCTGATTGACGGACTGACAATGCTCCAGTATCGTATGCAAAACGTGGTCCTTTCGAATGAATGAACCCTCAGTCCCTCCAAGCTGACCCACAAAAACTGGTACGTTTCTACAGCTGTTTGTTGTGCGAATGCAACTTATTGATACACAATGTGCACTGGAAATAAACAAGTCCGAGCTAATATTAACGGATTTTGTAAAATTTAATTGTGAAAAATAGCACTCGAAAAATGTACACCTACATAAATCTATATTTATTTAGGTACTATTCATTAAAGAGCTTATTTCTCTTGCAACATATTCCATTGATTCAATTTAAATTTGTCTCAGTGCAAATGCGTTTTTTATTCATTTCATTCATATCATAAACGCTGGCATATTAACCCCACTTAGCCGGCTTTTTGAGTCAGCGATCGAATTTCCAGGCAGCTCGATTAACGCATGTGTTGAATTAAAAAAAAAAAAAAACAACCAAGAGAATTTATAAGTTGCACTTTTATTTTACGAGAGAATGGGAGGGGGACTCCCCCAGACGTTTTAGTCCTCGAACTTTTTAATAACGATCATTTTCATTTCATTTACGCGTGCCCGCGTCGCTGATCGTCTCGATAAGGAAAGTCGGGCTGGTGGGCAGGTTCTGTGGCCGAGGGTCGCTACTGTCCCAGTCAACTGGACTGTGGCCCGTGCGTGGTTACCCCAATTAAGGACCTCGTCCTGGACAAAGTGTCGCCTCCTGCTGTTTGGCGCTAGCCCAGCTGACGTGTGGCTGCCTATGTGACTGGCTTATCAGTTGATCATCATCGGCCAGAATGATTAATGCCGGGGGGATATGAATACGAGTATGAGCACAGCAACATTGCTGAGTGATCGTTTAATAGTTTGAGCCGACTTTCTCCCGGCGGAGCTCGGCTTATTTTGACAGTTGCGCTTACGTTTTTAATTAGTCGCTGGGCTTTCTCTGCAGCCTGTACTTAATTACGATTCAGTTGGGCGAGCGAGCGGGGGATTCGAAAAAGTTGCGCAGCCAGATAGCAGGAAAAAACCATTGAAGAGGTGTAACCCGATATGCTTGTGAGTGGACTGGAAACAATGGGCAACGGCGAACGGAAAGGGTGCTCCTGCATTGTCCTTTTCTCCCAGGATGACGCAAAAAGCAGACGATGACATTATAATTACACACACACATACACATACAGAGTAAGGTATACATAGAGTAATTACAATCCAATTGCAATCGCAATGGCAATTGAGGACCTAACCAATCCCATAACATATCTCTTCATCTGCAACTGATTTTCGGCGCTGAGGGGATTAGTGTTTAGTGGTGAAATGCCTTTGATTCCTTATCGCGATGTTGTGGTGGGAACTTCTATGGTCGCAATTTAATCAAAACATATTCTGCAGACCATCGGATGCATCCAATCTGAGTCTGCGGCTTGACTTCACCCCAACCTCTCGGATTCGCCGGTCACGTGTCATTTGGCGGGGCTTCCCATGGTGGCAAATCGACAAAAGATGAAATAATAGCAAAAAACCAATATCATGCTCTTCACAAATGTCACCATTTTCGGTTACTTTGTTTAGTCGCCTCAGATCAGTGGGACATAGCCTAAGCCGCTCCCCAGGCACTAGACTATTGCTAATAATCCCGTTTAATGACAAAAGCAAACTTCGCTGCCCATTCGAGTGTTTAATATTTTGCCTACTTTTGCGGCCAGGTCGAGTATGCCTCGAAAACCGTTCGAGAACCCCTCGAAAACTGCTCGAAAACCCGTACCGTTAAATGTCAACAATGTAACATAAATTCCTGGTATCGGAAGGGGAGTACGGAATTTCGGAAGGGGCGATCCCGCACGGGATGGACCAATTAGCGTGTGCAAATCTTTCATGCATGAGCGATTCCTAAGCGGTTTTAGGGCTCACAGATCGGTTGGCCACACAAATTTAAATAGATTTATTTAAATCAATTTCGCTAATGCGACAATCGTATGAAAAGTGCGGGTAATAACATTTGAATTGGTTAATACTCCACTCGTTGCTTAACTTAACCCCAGCCACACGGTTCACATCACTTTGAACTTTCGCTTGGATCTCGACACAAAGAAAGCCCCACGGATGGCTCGGGGACATCAAAGCCGAAACTCATAGCCAACCAGAAACCGATGTTCGACGCCATGTTAAACAACTCAATTGCACAGCCCATTCTATGCCTTCATGCTCTATGATGCCAAGGACAAAGGGATCCCAAGTCGCGGAATTATGATGGGTGAGCCGGGGCGAAAGGAGCCCAAAGCGAGAACCGCAAACAATTCATTAAAAGCTAAATAACAAATGCATCAACCCCCCCTAAATATCCTCCCCATTTGACAGCCCGGGGCTGATTGGAGGTCTACGAGGGTCCAAAATGGGAGCAGGAGTGACCCGAAGCACCGCACCCACTTCTAAAAACATGGCCGTCCGCTTCCGCCGCAGCATGACACCAATGCAAATGGTCGTGGAAATGAATACCTAGCTGTCCGCGGTTTGCCGTGGGCAAATTTATTCAGTACTTATTTCATTAACCGCGACGAGCTCTTGATTTGCGTAATTAGCCGAGCAAATAGCTACAAGCTTTTGTTTTGATTCTTCATGGCACAAATTAGCCCCAGTAATTGAGGTAATTTCTTTTGTCCTTTTATTTGCCTTCATCTTGTGCCAGAAAATGGGATGAAATATGGGTGTTCCTAATTCCGGCTGTACCATCTTATTATAAATATATTTTAGTAAAGTCTAATACACTAATTCATTCAACATACATTCATCATTCCTAATCTTCTAAATTACCTATAAAATCACAAAATAGGTAGTTTTTACTGTATCATATCATATTCTAGTATTTTTCCATGCCTAAGTCAGATTTTTCTCGACGTGCTCGTAACTTGAGAGGACTTCCTTCTATTTTCGAGTTTCTGCGGCTGTTTGGGGTCTGGCTTCTCGGTGGGTCGAAACTAGCCGAAAGCCAAAGCGGCTTTCTCTCAATTGCCGCTGTAAACATGAAGCCCATTAGAAGTGATTTGAGCTGGCGACTTGGGGAAGCCCCTGAAGGCTCCTCCTCATAATTCACCAGTCCGGGCTGAAAGTAAACTTAATTGAAAATCATTACTGCTGGCAAGTGAAAATGGAAGTGGGAATCGCTGCAAAGAGAGCGACTGTGGCTATCGCCCACCTGGCTATTGATTTCCACACCTGATGCACCCTTGGCCGCAGCGAAAGAGGTCAACTAAATGTTAATGTCACACACACACATTCTGGCTTTTCTGTCTGAGGTTCGGTTGCAGTTGCACCCTCGAAAAAAAAAGAAATCACAGTCCAAGCACGGGTCACCTGCCCAAAGGGTCAAAGTTTGTCAGGGGGTAGAGCTTAGTCCAACCGCCCGGTGAAAGCGAAATGCGAAAGCAAAACGAGCTCAAGGGGTAGGCACTATAGAATACCATTCCATGCCACACCATATGCTACAAATTGGCATTTTAGAACGGTGAGAATGCATTTCGTGCGGCTTACATTTAACACCAAAGTTCAGTGGGTGCGTGGGAAGCTTAAGAGTCGATAAATAAAATGAATCAATCACAATCGTGGGACATGAGCAACTTTGGCCAATTACATTCGCCCCGATTTCACCAGTCGCAAAAAAAAGAACTGAAAAATCACATCCAACTAACGCTCCTAAATGCGAATATAGAACACATTATAAGGAAAAGTGTTTCGCCTTGGCAGCATAAATAAATAAAATGTACTTATAAAGATGCTTTTAAGCCAGCAAGTTAAGAAGGTTACATACACAGCTGCACAGAGAAAAAACAAGTAAAACTGGTTCGTTGAAAATATGTAAATCAAAAAGTATACAAATCCTGATATATAAGTATATAAGTTGTAAATTTACAACTGCAGATTGATATTATTTGGAAAATTCATTTAAGAAAATGTTGATACATTTAAATAGTAGGTAAATATTTTTACAGTGTGTATTTATACATATATATACTGTACAGGCAGGGTTGAGTGGGCCAAATTCTTAACAGCTGTTGTCAGTTATGGGGTTGTTAAGGGTCGCCAGCCTCCTTGATTTTCCATCGTTTTTCCCTCCGGCGAACTTTGATGCTTCAACTTTCTTAGGCTGAACAACTTTTGGCCGTCGGCAAAAATGGTAAATGCCTAATGGCCTCTTAAGTTCGGGCCCGCATTACCGGAATGGGGCCTTTTCACGTCTTGATTTTCGGGCAATCATCAGAATGCATAATTGATGGCGTTATTAACCAATATTTTCGCTTCTCTCTCCTTGCAG
Seq C2 exon
ATTGGGTTTCATATCGCAGTGGGGAGCGTTGGCCGGTCGCTATGCCGCCCTGTGTCCGCCCGGATGGCCCTGGGCCCCCCAGCGACTGCCCTTCCACAGTCCCACCCATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0264005:FBtr0330385:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.957 A=NA C2=0.500
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0303412
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0303411, FBpp0312056
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)