DmeINT0022849 @ dm6
Intron Retention
Gene
FBgn0025874 | Meics
Description
The gene Meiotic central spindle is referred to in FlyBase by the symbol DmelMeics (CG8474, FBgn0025874). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:13962658..13964702. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr3L:13962658-13964702:-
Coord C1 exon
chr3L:13964119-13964702
Coord A exon
chr3L:13964014-13964118
Coord C2 exon
chr3L:13962658-13964013
Length
105 bp
Sequences
Splice sites
5' ss Seq
AAAGTAGGT
5' ss Score
6.84
3' ss Seq
AATTTAAATTTATTTTTTAGTAA
3' ss Score
6.15
Exon sequences
Seq C1 exon
TACGTTCACATTGACTACTTGGCAGGAGAGCAAGTGCCCAACATTTGTTGATTCTTTTGAAATTCCGGCCTCTATGGTTGGGAGATCATCGGGAAAAATGGAAAGATCAGTGGACGCCAGCATGGGAAAGAACTGCCGAGCCTGCGCCGAACACTCATCCATACTGGTGGACCTTTTCTCCAAGGAGATCTCTGATCCCCCCATTTGGGAAATGTTGAACTCAATTCTGCCGGAGATCTGTCGCGTGAAACGGGATGAAATGCCACAAAAGATCTGTCCTACCTGCCTGGTGGCCGCTCAAAATGCCTTTCACTTCCGTCACAAGTGTGAGCAGAGTTTTCAGTTCTTTTCCCAGCTCCTCCAGCTCGATAAATCAAACTCAAATCTGAGTAGATCCCATTGCAGAAGAGGTACTATGAACCCATTAATACCCTTCGAGATAGTTGGTTGCGAGGATCCATTGGACACAAATGTAACCAAATTGGACGCTAATCGGCCTGATGTAAAAACTGATATCGATGAGCCAACCGATGGAAAGGCAACTAATGGTCAGGAGAGTGAACCATTGCAAGAAGTTTTTGAAA
Seq A exon
GTAGGTCTATTCGATGTCATCCACTTTCACAAGAACTTCCATTGTACTGCTAAAATCTATTCTAGACTTGCCCGTTATATGCTAAAATTTAAATTTATTTTTTAG
Seq C2 exon
TAACAATGAACGATATTAAAACGGAAGATGAAGTATCCATTCAGGAGACATTTGAAGATGCCTTTGATGAAGAAAATGATAATAACAATACTGATAGCGAAAGGGAGGATTCAGACCAATGGACAGTGGGCTCGACTGAAGACCAAGATGAACCCTGGATTCCCGGCGGCGGAGGGCGCCAAACGGTTGGCGGCAATAATCAATCGCTTCTGTGCACAGAGTGTGGAGTGAGTTACTCGACTCAAAAGGCGTTGGCAAGGCACGTTGCCAAGCACAAGGAGCAAGGTGATACACAAAAGCCGCACCTCTGCGATTTCTGCGGTCGGGGATTTCGTACCAATGCCCAGCTAACGACCCATAGACGCCGTCATACTGGAGAGCGTCCTTTTAAATGCCCCCTCTGCCCGAAAGCTTATACGCACGGTCCGACTCTGAAGTCGCATATGCACACCCACGACGAGGAAAAGGGTCACAAATGTCCACAGTGCGACAAAACCTTTTACACGAGAGGCAATCTTAGGGCCCATATACAGAGGCACACTGGCGAACGACCCTATAAGTGTCCCGACTGCCCACAAACCTTTGCCAAAAACTCTGGCCTTAAGTTGCATAGCCGTCTGCACAAGGAAGAGCGACCCTTTAAATGTGAGCTCTGCGGCAAGGGATTCGTACAGAACCAGCATTTGATTACCCATTTGCGGGTCCACAACGGGGATCGCCAGTTCAAGTGCCCCGACTGCGACAAGTCGTTCTTCGAGAAATCGAACATGATGAAACATCAGCGAACCCATTCGGGTATAAAGCCATTTAAATGTGAGGAGTGCGGCCAAGCCTTTTCCCACAACCATCACCTTAAGAGTCATCTACGCATCCATACAGGCGAAAAGCCCTACAAGTGCGACCAGTGCGGCAAGGGTTTCAGTGCGAATCAGTCACTGATGAAGCATACCCTTTGGCACGTGGACAATAATGATCGGCCATTTAAATGTTCTCAGTGTCCCAAAGCCTATGACACTCAGCAGAGCTTACGGGGTCACGAGAAGACGCACAAAAACCCGGATGAGCCAAAAACGCTGCACCAATGCCCGCACTGCGACGTCAGGTTTGCTTTAAAAAAGACCCTGGATAAGCATATCACAAGCCACAAGATTCGACCCCACCCATGCCCGCAATGTCCAGAGGGATTTTTCTCCCAGAAGAGCTTAAAAAAGCACTTGCGACTTCACAACCTAAAGAAATAATATAAGATTATCCTGTAGCCCCAGCATAAGACCATTAGTTATAATAAGTGTTAAGTAGATATAACTACAGACTTCGTGTAAGGAAATCATTAAATTTGAACAATCTGATGTTACC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0025874:FBtr0075791:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.274 A=NA C2=0.337
Domain overlap (PFAM):
C1:
PF0777610=zf-AD=WD(100=44.4)
A:
NA
C2:
PF134651=zf-H2C2_2=WD(100=7.2),PF134651=zf-H2C2_2=WD(100=6.3),PF134651=zf-H2C2_2=WD(100=6.3),PF134651=zf-H2C2_2=WD(100=6.3),PF134651=zf-H2C2_2=WD(100=6.3),PF134651=zf-H2C2_2=WD(100=6.0),PF134651=zf-H2C2_2=WD(100=6.3),PF134651=zf-H2C2_2=WD(100=6.3),PF134651=zf-H2C2_2=WD(100=6.8),PF134651=zf-H2C2_2=WD(100=7.0),PF0009621=zf-C2H2=WD(100=5.6)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0075533
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0305244
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGTTGCGAGGATCCATTGG
R:
GGTCTGAATCCTCCCTTTCGC
Band lengths:
258-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)