DmeINT0023045 @ dm6
Intron Retention
Gene
FBgn0039581 | Moca-cyp
Description
The gene Moca-cyp is referred to in FlyBase by the symbol DmelMoca-cyp (CG1866, FBgn0039581). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:28340334..28345169. Its molecular function is described by: cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization; protein folding; mRNA splicing, via spliceosome. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chr3R:28341372-28342214:+
Coord C1 exon
chr3R:28341372-28341459
Coord A exon
chr3R:28341460-28342184
Coord C2 exon
chr3R:28342185-28342214
Length
725 bp
Sequences
Splice sites
5' ss Seq
TATGTAAGT
5' ss Score
6.69
3' ss Seq
TCTTCTGTTTCTCATTGTAGTAC
3' ss Score
8.63
Exon sequences
Seq C1 exon
ATGAGAGCTTCGAAAAGAAGCACGATCGTCCCTTCCTGCTGTCGATGGCCAACCGGGGCAAGAACACAAATGGCTCGCAGTTCTTTAT
Seq A exon
GTAAGTGCTCTCGACGGAGGACCGTAACCGGCTGGTCCGGACTAACGTGGCCGTAAATTTAGTTTCAGTTCTGTTTCAGGCACCGATATTACAGCTAAACTCTCTTCGTCTTCTTTTTGATCTATACTTAAACCACTGTTGTTGTTCATTAATCTATTGCCATTTAGCCTTAGCCCGTGGGCGTTAAAGTGTGAGCTAGCGTCCCACTGACCAGCGGACAGATGCATCGCAATCTGTCCTCCATCGGCCGATGCACCGCCATCCCAGCATCCCTAGTGCATTTGGTCTGTGGGTCCAAAAACCAAGCGAAAGACGATGCAGGTCTTTCAGCTCCATGGTCTTTGGTCCCTGGGCCTGGGTCTCAGTGTGTGTCTCAATCTCTCTCTCTCTCGCTGTCGGCTCCTTGTGGATCTTTGCGGGAATCTTGGGCTGGATCCTCACGATGGATCTGCCAGATGACAATGTGCTGGCCATGGCCAGCGGCAGCGGCTCTTGCGGTTGGTGGCTTGCCAAAATCCTGTGTGCCACCTCTGCCTACACACCTAGAAACCTTTAAACTTTGTTGCACATGACATTGTCTCCGCCACAACCGACAACAATAACAACAACAACAACTGAAACAACAACAACAACACCGATTTCAACTACAACTGCCTACTGCAGCCCAACAACCAGTTAGCCAAAGTGTAAAGAATATTTTTCTCTTCTTCTGTTTCTCATTGTAG
Seq C2 exon
TACAACACAGCCTGCGCCACATTTGGACAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0039581:FBtr0085286:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.333 A=NA C2=0.273
Domain overlap (PFAM):
C1:
PF0016016=Pro_isomerase=FE(17.5=100)
A:
NA
C2:
PF0016016=Pro_isomerase=FE(6.0=100)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0084655
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)