DmeINT0028168 @ dm6
Intron Retention
Gene
FBgn0030503 | Tango2
Description
The gene Transport and Golgi organization 2 is referred to in FlyBase by the symbol DmelTango2 (CG11176, FBgn0030503). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:13616989..13619207. Its molecular function is described by: . It is involved in the biological process described with: Golgi organization; protein secretion. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages.
Coordinates
chrX:13616989-13617936:+
Coord C1 exon
chrX:13616989-13617575
Coord A exon
chrX:13617576-13617813
Coord C2 exon
chrX:13617814-13617936
Length
238 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
3' ss Seq
TATGTATTCCCCCATTTCAGGGA
3' ss Score
9.59
Exon sequences
Seq C1 exon
CAAAACAAAACAAAAACAAAATTAAAAGAGAAATCAAAACAAGGCAACCCGGTCATTGAAATTTCAGAAAATACTGCTTTGTTTGCGTTAACGGGAATGCTTTTTGCCCCGTAGATATGTATATATCACATAGAGGCACGGCTCACAGAGAACACCCACCAATCCAAACCATTTACATTTACCACTTAGATTAGCTGGTCTCGCAAACAACGGATAAGACTGTATATCAGCTGTACGTACGTACGGCTATTTGGTGATAAAACCGGCGCTATAGTTCCACTGCCACAAAGTAACAAAGAGAAGACTGAGCCGAACAACCTGCCATTTTGATACCGACGCCCCACCGAGATTAAAGCCCACTTTTCCGGATCCCATTCGCAGTTGTCCCACAACCTCAAGGCACTACAAATCGCAACAATAGCCAAATAAGTATAGGATTCCGACGATGTGCGTGATATTCTTTTGTGCGGACTCGAATCCGCAACCGGGTGGCTACAAGCTCATCCTGGCCTCCAATCGGGACGAGTTCTTTGCCCGCGCCACCCTATCGGCAGCCAAGTGGGCGAATGCCGATCATGTTTACGGAG
Seq A exon
GTAAGTGGTGGGGCTTATGCCCTTGAATGCCTATGCTTAGATGGAGTATAATCCTTGAGAGCTTGTATTCATCAAGATGTTACCTATAGTTTAGTCACTAAGATGATTTGATAGCAGTTTGTTAGAATGAACACCTCTCACAAGATCTGTTTCCCAGCAACCTAATTGGATTTCAAGCCATCTTACCCATGAGTGCGGGATCAACTTGAGTAAATATTTATGTATTCCCCCATTTCAG
Seq C2 exon
GGATCGATCTGGAGCCGGGACGCGAGGGCGGCACCTGGCTGGCGATCGGCCACTCCGCTGGCTTCTTTAAGGTGGGCGCCCTGCTCAATCTGACCGGCGAGCCCAAGCCACGCGATGCAGTTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0030503:FBtr0073807:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.048
Domain overlap (PFAM):
C1:
PF057427=NRDE=PU(17.0=97.9)
A:
NA
C2:
PF057427=NRDE=FE(14.8=100)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0300867
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0073638, FBpp0304111, FBpp0309341
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTCCGGATCCCATTCGCAG
R:
TTAAAGAAGCCAGCGGAGTGG
Band lengths:
297-535
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)