DmeINT0030956 @ dm6
Intron Retention
Gene
FBgn0262029 | d
Description
The gene dachs is referred to in FlyBase by the symbol Dmeld (CG42840, FBgn0262029). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:8466817..8488671. Its molecular function is described by: motor activity; actin filament binding; protein binding; molecular adaptor activity. It is involved in the biological process described with 11 unique terms, many of which group under: imaginal disc-derived appendage morphogenesis; establishment or maintenance of cell polarity; vesicle cytoskeletal trafficking; negative regulation of biological process; post-embryonic development. 35 alleles are reported. The phenotypes of these alleles manifest in: visual system; peripheral nervous system; epidermal cell; prothoracic bristle; adult head sensillum. The phenotypic classes of alleles include: phenotype; increased mortality; fertile; some die during P-stage.
Coordinates
chr2L:8486022-8487902:+
Coord C1 exon
chr2L:8486022-8487681
Coord A exon
chr2L:8487682-8487744
Coord C2 exon
chr2L:8487745-8487902
Length
63 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
3' ss Seq
CCCCAAACTCTATGATGCAGTAC
3' ss Score
1.91
Exon sequences
Seq C1 exon
GGTCTCGAGGTGGATGTGAAGGGTGAAACGGAGCTGAACTCTGTGGCCAGTCTACTTGGCGTTCCGCCGGCGGCCCTCTTCCGTGGATTGACCACCCGTACCCACAACGTTCGTGGCCAGCTGGTGAAGTCCGTGTGCGGCGATGGCGATGCCAATATGACGCGGGACTGCCTGGCAAAGGCGCTCTACTGCCGCACGGTGGCCACTATTGTGCGGCGGGCCAACAGCCTGAAGCGCCTGGGATCCACGTTGGGCACCCTCAGCTCGGACTCAAACGAATCGGTGCACAACCAGGCGGATGTCGCCTCTCAGCACGCCTCCACCATTGGCGGTGGCAATGCGGGCTCCAAGTCGATGGCGGCACTCAATAATGCAGTGCGCCATGCCACCTCCGATGGCTTCATTGGAATCCTGGACATGTTCGGTTTCGAGGAGCCCTCGCCACATGCCCATCTGGAGCACTTGTGCATCAACCTGTGCGCCGAGACCATGCAGCACTTCTACAACACGCACATCTTCAAGTCCTCCGTGGAATCCTGTCGCGACGAGGGCATCGTTTGCGACACCGAGGTGGACTATGTGGACAATGTGCCCTGCATCGATCTGATATCCTCGCTGCGAACCGGTCTGCTCAGCATGCTGGATGCAGAGTGTTCGGTTAGGGGCACTGCCGAGAGTTATGTGACCAAGTTGAAGGTGCAGCATCGCAGCTCCACTCGCTTGGAGACGAAACCCACAGCCGAACCACACGATCCACGCATGTTTCTCATCCGTCACTTTGCCGGTCGGGTGGAGTACGATACCACGGACTTTCTGGACACCAACCGTGATGTGGTGCCCGACGATCTGGTGGGTGTCTTCTACAAGCACACCTGCAACTTTGGCTTCGCCACCCATCTCTTTGGATCCGAGCTGAAAGCCCTGTATGCTCAGCAACAGGCTCCAAGGGGTCTGAGCTTCCGGATCTCGCCCACATCACACTCGGATCTGCTGAACGGGGACGAGCCGGTGTCCACGCTGACCCAAGACTTCCACACCAGGCTAGACAATTTGCTGAGAACCCTGGTGCACGCCAGGCCGCACTTTGTGCGCTGCATCCGAAGCAATGGAACCGAGGCGGCTCGCAGCTTTGATAGGGCTACGGTGGTGCGCCAGATTAGATCCCTGCAGGTCCTGGAGACGGTCAATCTAATGGCCAGTGGGTTCCCGCATCGCATGCGCTTTAAGCAGTTCAATGCCCGCTACCGTATGCTAGCCCCATTCCGCCTCTTGCGCCGCAGCGAGGACAAGGCTCTGGAGGATTGCCAGTTGATTCTGAAGTACGCAATGGAGCAGCCGCCAGTGCTGGATGGCTCGGTGACCCTGGCCTGGGCACCTGGCAAGCGTCATGTCTTCCTTAGCGAGGGCATTCGCCAGCACTTGGAGCACTTGCGCACCGAGATCAGGCACAAGAGCGCCACCCTGATGCAGGCCACCTGGCGAGGCTGGTGGTGGCGCAAGAAGATGGGCAATGGCGGGGCCAAGCGCTCCAAAATCCCAGGTCTTCAACAGGCGCCACTGCCGAACAACAAGACCACGCCGAACTCCGCCGCACAGAACAAGGCCGCATCCTCCACAATGGCCGCCCTTGCCGCTGTGGCAGCTGCTGCTCCCATTTCTG
Seq A exon
GTGAGATTCCCCCACGGGTATACCCATTCTCCGCCCATCTAATCCCCAAACTCTATGATGCAG
Seq C2 exon
TACCACGCCTCTCGGCCAAGACAACGAGCCTGGGCATTGGAGGCACTGTGGCCAGACCAAGGCCACAGCCCATTGCTGGGACTCCTCCGCCGGATCCGCAGGAGAAGTGCGACCAGAAGATCATTCAGCAGACCTGTAACCTGTTTGGACTCGATTTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0262029:FBtr0303923:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.106 A=NA C2=0.679
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(63.5=84.1),PF0061222=IQ=WD(100=3.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0292925
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0292924
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACTGCCGAACAACAAGACCA
R:
CTCGTTGTCTTGGCCGAGAG
Band lengths:
133-196
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)